Literature DB >> 25540825

Aqueous based synthesis of antimicrobial-decorated graphene.

M Haniff Wahid1, Uwe H Stroeher2, Ela Eroglu3, Xianjue Chen4, Kasturi Vimalanathan5, Colin L Raston6, Ramiz A Boulos7.   

Abstract

Ramizol® (1,3,5-tris[(1E)-2'-(4'-benzoic acid)vinyl]benzene) is a potent amphiphilic anti-microbial agent. It is essentially a planar molecule and can interact with the surface of graphene via extended π-π interactions. Herein we demonstrate the utility of Ramizol® in potentially acting as a molecular 'wedge' to exfoliate graphene and stabilise it in water. The non-covalent attachment of Ramizol® on the graphene surface enables release of Ramizol® by altering the pH of the solution. Furthermore, the stabilised composite material demonstrates antibacterial activity against Staphylococcus aureus which leads to potential in biomedical applications with graphene acting as a drug carrier as well as enhancing the structural strength of the composite material.
Copyright © 2014 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  Antibacterial; Antimicrobial; Exfoliation; Graphene; Non-covalent functionalization; Ramizol; Ultra-sonication

Mesh:

Substances:

Year:  2014        PMID: 25540825     DOI: 10.1016/j.jcis.2014.11.043

Source DB:  PubMed          Journal:  J Colloid Interface Sci        ISSN: 0021-9797            Impact factor:   8.128


  5 in total

Review 1.  Carbon Nanomaterials: Synthesis, Functionalization and Sensing Applications.

Authors:  Giorgio Speranza
Journal:  Nanomaterials (Basel)       Date:  2021-04-09       Impact factor: 5.076

2.  A Review on Graphene-Based Nanomaterials in Biomedical Applications and Risks in Environment and Health.

Authors:  Thabitha P Dasari Shareena; Danielle McShan; Asok K Dasmahapatra; Paul B Tchounwou
Journal:  Nanomicro Lett       Date:  2018-05-21

3.  Synthesis, Characterization, and Bactericidal Evaluation of Chitosan/Guanidine Functionalized Graphene Oxide Composites.

Authors:  Ping Li; Yangyang Gao; Zijia Sun; Dan Chang; Ge Gao; Alideertu Dong
Journal:  Molecules       Date:  2016-12-23       Impact factor: 4.411

Review 4.  Roles of Bacterial Mechanosensitive Channels in Infection and Antibiotic Susceptibility.

Authors:  Margareth Sidarta; Luna Baruah; Michaela Wenzel
Journal:  Pharmaceuticals (Basel)       Date:  2022-06-21

5.  Preclinical development of Ramizol, an antibiotic belonging to a new class, for the treatment of Clostridium difficile colitis.

Authors:  Shasha Rao; Clive A Prestidge; Lynn Miesel; Deb Sweeney; Dean L Shinabarger; Ramiz A Boulos
Journal:  J Antibiot (Tokyo)       Date:  2016-05-18       Impact factor: 2.649

  5 in total

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