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Literature DB >> 25540392

Molecular profiling of Escherichia coli O157:H7 and non-O157 strains isolated from humans and cattle in Alberta, Canada.

Linda Chui¹, Vincent Li², Patrick Fach³, Sabine Delannoy³, Katarzyna Malejczyk⁴, Laura Patterson-Fortin², Alan Poon², Robin King⁵, Kimberley Simmonds⁶, Allison N Scott⁶, Mao-Cheng Lee⁷.

Abstract

Virulence markers in Shiga toxin-producing Escherichia coli (STEC) and their association with diseases remain largely unknown. This study determines the importance of 44 genetic markers for STEC (O157 and non-O157) from human clinical cases and their correlation to disease outcome. STEC isolated from a cattle surveillance program were also included. The virulence genes tested were present in almost all O157:H7 isolates but highly variable in non-O157 STEC isolates. Patient age was a significant determinant of clinical outcome.

Entities: Species

Mesh：

Substances：
Virulence Factors

Year: 2014 PMID： 25540392 PMCID： PMC4390646 DOI： 10.1128/JCM.03321-14

Source DB: PubMed Journal: J Clin Microbiol ISSN： 0095-1137 Impact factor: 5.948

25 in total

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Authors: Laura Heinisch; Katharina Zoric; Maike Krause; Herbert Schmidt
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