Literature DB >> 25539235

Mediastinal lymph nodes and pulmonary nodules in children: MDCT findings in a cohort of healthy subjects.

Giordano Rafael Tronco Alves1, Edson Marchiori, Klaus Loureiro Irion, Marcos Duarte Guimarães, Carol Fernandes Jerzewski Sotero da Cunha, Vinícius Valério Silveira de Souza, Bruno Hochhegger.   

Abstract

OBJECTIVE: Existing data are very limited on incidentally detected pulmonary nodules or mediastinal lymph nodes in healthy children who undergo chest MDCT. We aimed to evaluate the prevalence, distribution, and average dimensions of these occasional findings in a cohort of otherwise healthy patients.
MATERIALS AND METHODS: Two radiologists reviewed in consensus the scans of patients referred for chest MDCT during the preoperative workup for pectus carinatum or pectus excavatum treatments. Exclusion criteria included the presence of any documented malignancy (by date of MDCT or during the 2 years after the examination), history of recent infections, or trauma. Patients' records were assessed after 2 years for the development of any malignancy.
RESULTS: A total of 99 individuals (63 boys, 36 girls; mean age, 13.5 years; range, 4-18 years) who fulfilled the study criteria were evaluated. The presence of at least one pulmonary nodule was observed in 75% of the patients, with a mean diameter of 2.8 mm. Of a total number of 225 pulmonary nodules, only 24 (10.7%) were calcified. Mediastinal lymph nodes were also identified in 81% of the cases, with a maximum diameter of 7 mm (smallest axis).
CONCLUSION: The presence of pulmonary nodules or mediastinal lymph nodes on the basis of preoperative chest MDCT scans in healthy children is frequent. Given that 95% of the nodules and 100% of the lymph nodes measured less than 6 mm and 7 mm, respectively, we conclude that incidental findings under these limits are very unlikely to be pathologic.

Entities:  

Keywords:  CT; pectus carinatum; pectus excavatum; pediatric radiology

Mesh:

Year:  2015        PMID: 25539235     DOI: 10.2214/AJR.14.12773

Source DB:  PubMed          Journal:  AJR Am J Roentgenol        ISSN: 0361-803X            Impact factor:   3.959


  2 in total

1.  Frequency and characteristics of pulmonary nodules in children at computed tomography.

Authors:  Atia Samim; Annemieke S Littooij; Marry M van den Heuvel-Eibrink; Frank J Wessels; Rutger A J Nievelstein; Pim A de Jong
Journal:  Pediatr Radiol       Date:  2017-09-04

2.  Ultra-low-dose chest computed tomography without anesthesia in the assessment of pediatric pulmonary diseases.

Authors:  Cristina Manera Dorneles; Gabriel Sartori Pacini; Matheus Zanon; Stephan Altmayer; Guilherme Watte; Marcelo C Barros; Edson Marchiori; Matteo Baldisserotto; Bruno Hochhegger
Journal:  J Pediatr (Rio J)       Date:  2018-09-17       Impact factor: 2.990

  2 in total

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