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Literature DB >> 25538810

A novel microfluidic flow focusing method.

Abstract

A new microfluidic method that allows hydrodynamic focusing in a microchannel with two sheath flows is demonstrated. The microchannel network consists of a T-shaped main channel and two T-shaped branch channels. The flows of the sample stream and the sheath streams in the microchannel are generated by electroosmotic flow-induced pressure gradients. In comparison with other flow focusing methods, this novel method does not expose the sample to electrical field, and does not need any external pumps, tubing, and valves.

Year: 2014 PMID： 25538810 PMCID： PMC4241768 DOI： 10.1063/1.4899807

Source DB: PubMed Journal: Biomicrofluidics ISSN： 1932-1058 Impact factor: 2.800

18 in total

Review 1. Micro total analysis systems. Recent developments.

Authors: Torsten Vilkner; Dirk Janasek; Andreas Manz
Journal: Anal Chem Date: 2004-06-15 Impact factor: 6.986

2. Pinched flow fractionation: continuous size separation of particles utilizing a laminar flow profile in a pinched microchannel.

Authors: Masumi Yamada; Megumi Nakashima; Minoru Seki
Journal: Anal Chem Date: 2004-09-15 Impact factor: 6.986

A novel microfluidic flow focusing method.

Review 1. Micro total analysis systems. Recent developments.

2. Pinched flow fractionation: continuous size separation of particles utilizing a laminar flow profile in a pinched microchannel.

3. Beads and chips: new recipes for analysis.

4. One-dimensional acoustic standing waves in rectangular channels for flow cytometry.

5. Focused electrophoretic motion and selected electrokinetic dispensing of particles and cells in cross-microchannels.

6. Three-dimensional hydrodynamic focusing with a single sheath flow in a single-layer microfluidic device.

7. Analytical performance of an ultrasonic particle focusing flow cytometer.

8. Continuous flow two-dimensional acoustic orientation of nonspherical cells.

9. A hard microflow cytometer using groove-generated sheath flow for multiplexed bead and cell assays.

10. Sub-micrometer-precision, three-dimensional (3D) hydrodynamic focusing via "microfluidic drifting".

1. A Microflow Cytometer with a Rectangular Quasi-Flat-Top Laser Spot.