Viroj Wiwanitkit1. 1. Hainan Medical University, China, Nigeria ; Faculty of Medicine, University of Nis, Serbia, Nigeria ; Joseph Ayobabalola University, Nigeria.
Sir,The recent report on N-acetylcystein (NAC) in dengue hepatitis is very interesting.[1] Habaragamuwa and Dissanayaka they found that NAC resulted in a good outcome without hepatic transplantation.[1] In fact, hepatic dysfunction is an important, but forgotten complication of dengue.[2] The management of dengue hepatitis is usually supportive and symptomatic treatment. The use of NAC might be useful. However, it should be noted that dengue hepatitis can be self-limited.[34] To manage dengue hepatitis, with or without hepatic dysfunction, the critical concept is optimal fluid replacement therapy.[5]
Authors: Maria Paula Gomes Mourão; Marcus Vinícius Guimarães de Lacerda; Michele de Souza Bastos; Bernardino Cláudio de Albuquerque; Wilson Duarte Alecrim Journal: Braz J Infect Dis Date: 2005-05-09 Impact factor: 1.949