Literature DB >> 25537166

Halide inhibition of the copper-catalysed azide-alkyne cycloaddition.

Rebekah M Moorman1, Matthew B Collier, Bram H Frohock, Michael D Womble, Justin M Chalker.   

Abstract

Chloride, bromide and iodide are inhibitors of the copper-catalysed azide-alkyne cycloaddition, with iodide exhibiting the most detrimental effects on rates and yields. A study of this inhibition is presented, along with experimental protocols to accommodate the presence of halides in this widely used reaction.

Entities:  

Year:  2015        PMID: 25537166     DOI: 10.1039/c4ob02479f

Source DB:  PubMed          Journal:  Org Biomol Chem        ISSN: 1477-0520            Impact factor:   3.876


  2 in total

1.  Ion-pair recognition by a neutral [2]rotaxane based on a bis-calix[4]pyrrole cyclic component.

Authors:  J Ramón Romero; Gemma Aragay; Pablo Ballester
Journal:  Chem Sci       Date:  2016-08-31       Impact factor: 9.825

2.  New 1,2,3-Triazole-genipin Analogues and Their Anti-Alzheimer's Activity.

Authors:  Patamawadee Silalai; Suwichada Jaipea; Jiraporn Tocharus; Anan Athipornchai; Apichart Suksamrarn; Rungnapha Saeeng
Journal:  ACS Omega       Date:  2022-07-06
  2 in total

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