| Literature DB >> 25536114 |
Emmanuel Ruggiero1, Javier Hernández-Gil, Juan C Mareque-Rivas, Luca Salassa.
Abstract
The Pt(IV) complex cis,cis,trans-[Pt(NH3)2(Cl)2(O2CCH2CH2CO2H)2] is photoactivated by near infrared light (980 nm) using NaYF4:Yb(3+)/Tm(3+)@NaYF4 core-shell upconversion nanoparticles. Coupling of this cisplatin precursor with the biocompatible PEGylated phospholipid DSPE-PEG(2000)-NH2 affords a valuable approach to decorate the surface of the nanoparticles, providing novel photoactivatable nanomaterials capable of releasing Pt(II) species upon NIR light excitation.Entities:
Mesh:
Substances:
Year: 2015 PMID: 25536114 DOI: 10.1039/c4cc07960d
Source DB: PubMed Journal: Chem Commun (Camb) ISSN: 1359-7345 Impact factor: 6.222