| Literature DB >> 25535792 |
Morven S Edwards1, Edwina J Popek, Brittany Wise, Lindsay Hatzenbuehler, Athis R Arunachalam, Amy B Hair.
Abstract
The usual route of acquisition for intrauterine herpes simplex virus (HSV) infection is transplacental. We evaluated a premature infant with in utero acquisition of HSV resulting from ascending infection. Histopathologic evidence of chronic chorioamnionitis and positive staining with immunohistochemistry for HSV in the placenta and umbilical cord established the diagnosis. The clinical presentation was also of interest in that the infant was initially healthy appearing.Entities:
Keywords: Ascending infection; chorioamnionitis; congenital infection; herpes simplex virus; in utero infection; intrauterine
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Year: 2014 PMID： 25535792 DOI： 10.2350/14-09-1548-CR.1
Source DB: PubMed Journal: Pediatr Dev Pathol ISSN： 1093-5266