Literature DB >> 25535580

Are breast cancer patients treated with radiotherapy younger now than ten years ago?

Marta Bonet1, Pere Godoy2, Maria Jose Cambra3, Encarna Mur1, Manel Algara4, Luis Fernandez5, Elsa Dalmau5, Àngels Arcusa6, Miquel Àngel Seguí5, Eugeni Saigí5, Sònia Gonzalez7, Lluís Cirera7, Josep Maria Solé1.   

Abstract

AIM: The aim of the present study was to analyze the age of breast cancer patients managed with curative approach at the time of treatment with radiotherapy.
BACKGROUND: Breast cancer is the most frequent neoplasm in women. Little is known with regard to the age of patients at diagnosis, and some authors have suggested that breast cancer is now affecting women who are younger than before.
MATERIALS AND METHODS: We performed a descriptive study of our series of breast cancer patients from 1998 to 2011. The age of patients, city of residence, year of treatment and uni- or bilateral location were extracted from the administrative database of the Radiation Oncology Department. The demographical and reference populational data were extracted from the Catalan Institute of Statistics.
RESULTS: 3382 patients were obtained. The mean age was 57.79 years. No statistical differences were observed in the mean age during the period of study (p > 0.05), nor in patients with bilateral neoplasias with regard to unilateral tumours (p > 0.5). Patients aged less than 30, 40, 50 and 65 years were 0.3%, 6.3%, 27.0% and 69.1%, respectively. The proportion of patients aged less, equal or more than 40 and 50 years was not statistically different.
CONCLUSIONS: Breast cancer patients treated with adjuvant radiotherapy after radical surgery have not experienced significant changes in their mean age at treatment. The subgroups of patients that remain out of the mammographic screening programmes were unchanged as well. The observed differences can be explained by demographical disparities and by a probable increase in the indications for adjuvant radiotherapy.

Entities:  

Keywords:  Age; Breast cancer; Epidemiology; Radiation therapy

Year:  2014        PMID: 25535580      PMCID: PMC4268594          DOI: 10.1016/j.rpor.2014.05.003

Source DB:  PubMed          Journal:  Rep Pract Oncol Radiother        ISSN: 1507-1367


  9 in total

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Review 3.  Early breast cancer in the older woman.

Authors:  Sonal Gandhi; Sunil Verma
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Authors:  María José Pérez Lacasta; Aleix Gregori Gomis; Misericòrdia Carles Lavila; Rosa Gispert Magarolas; Montserrat Martínez Alonso; Ester Vilaprinyo Terré; Roger Pla Farnós; Montserrat Rué Monné
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Review 5.  How effective are breast cancer screening programmes by mammography? Review of the current evidence.

Authors:  Doris Schopper; Chris de Wolf
Journal:  Eur J Cancer       Date:  2009-04-22       Impact factor: 9.162

6.  Estimation of an optimal radiotherapy utilization rate for breast carcinoma: a review of the evidence.

Authors:  Geoff Delaney; Michael Barton; Susannah Jacob
Journal:  Cancer       Date:  2003-11-01       Impact factor: 6.860

7.  Factors affecting 5- and 10-year survival of women with breast cancer: an analysis based on a public general hospital in Barcelona.

Authors:  Francesc Macià; Miquel Porta; Cristiane Murta-Nascimento; Sònia Servitja; Mònica Guxens; Andrea Burón; Ignasi Tusquets; Joan Albanell; Xavier Castells
Journal:  Cancer Epidemiol       Date:  2012-07-31       Impact factor: 2.984

Review 8.  Effect of radiotherapy after breast-conserving surgery on 10-year recurrence and 15-year breast cancer death: meta-analysis of individual patient data for 10,801 women in 17 randomised trials.

Authors:  S Darby; P McGale; C Correa; C Taylor; R Arriagada; M Clarke; D Cutter; C Davies; M Ewertz; J Godwin; R Gray; L Pierce; T Whelan; Y Wang; R Peto
Journal:  Lancet       Date:  2011-10-19       Impact factor: 79.321

9.  Recent increase of breast cancer incidence among women under the age of forty.

Authors:  C Bouchardy; G Fioretta; H M Verkooijen; G Vlastos; P Schaefer; J-F Delaloye; I Neyroud-Caspar; S Balmer Majno; Y Wespi; M Forni; P Chappuis; A-P Sappino; E Rapiti
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  9 in total
  1 in total

1.  Patient selection for partial breast irradiation by intraoperative radiation therapy: can magnetic resonance imaging be useful?-perspective from radiation oncology point of view.

Authors:  Marco Krengli; Carla Pisani; Letizia Deantonio
Journal:  J Thorac Dis       Date:  2016-09       Impact factor: 2.895

  1 in total

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