Literature DB >> 25535233

Localised bullous eruptions and epidermal detachment from the extravasation of hydroxyethyl starch (Voluven).

James London1, Stan Tay2, Brigid Brown2, Chasari Tancharoen3.   

Abstract

Extravasation occurs frequently with intravenous infusions. In this case report we describe the occurrence of epidermal detachment and multiple cutaneous bullous eruptions in a patient's forearm following the extravasation of hydroxyethyl starch (Voluven, Fresenius Kabi)-a colloid solution derived from corn starch, which is used to replace lost blood volume. The patient's affected body surface area was managed under the direction of our plastic surgical team. Despite a prolonged admission in hospital from other perioperative complications, he made a full recovery and was successfully discharged home. The probable pathogenesis relevant to extravasation of Voluven is discussed; as well as its management principles. 2014 BMJ Publishing Group Ltd.

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Year:  2014        PMID: 25535233      PMCID: PMC4275722          DOI: 10.1136/bcr-2014-207314

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  12 in total

1.  Bullous eruptions caused by extravasation of mannitol--a case report.

Authors:  K A Chang; B Jawan; H N Luk; S T Fung; J H Lee
Journal:  Acta Anaesthesiol Sin       Date:  2001-12

2.  Forearm compartment syndrome from intravenous mannitol extravasation during general anesthesia.

Authors:  Johnathan J Edwards; David Samuels; Eugene S Fu
Journal:  Anesth Analg       Date:  2003-01       Impact factor: 5.108

3.  Localized bullous eruptions caused by extravasation of commonly used intravenous infusion fluids.

Authors:  B J Robijns; W M de Wit; N J Bosma; W A van Vloten
Journal:  Dermatologica       Date:  1991

4.  Severe intraoperative acute compartment syndrome with bullous eruption complicating IV fluid administration.

Authors:  Jean-Louis Scholtes; Estelle Loriau; Bertrand Tombal
Journal:  Anesth Analg       Date:  2006-09       Impact factor: 5.108

Review 5.  Toxic epidermal necrolysis: Part I. Introduction, history, classification, clinical features, systemic manifestations, etiology, and immunopathogenesis.

Authors:  Robert A Schwartz; Patrick H McDonough; Brian W Lee
Journal:  J Am Acad Dermatol       Date:  2013-08       Impact factor: 11.527

6.  Extravasation injury in the perioperative setting.

Authors:  Wolfram Schummer; Claudia Schummer; Ole Bayer; Andreas Müller; Don Bredle; Waheedullah Karzai
Journal:  Anesth Analg       Date:  2005-03       Impact factor: 5.108

7.  Toxic epidermal necrolysis: effector cells are drug-specific cytotoxic T cells.

Authors:  Amal Nassif; Armand Bensussan; Laurence Boumsell; Aurelien Deniaud; Homayoun Moslehi; Pierre Wolkenstein; Martine Bagot; Jean-Claude Roujeau
Journal:  J Allergy Clin Immunol       Date:  2004-11       Impact factor: 10.793

8.  Hydroxyethyl starch or saline for fluid resuscitation in intensive care.

Authors:  John A Myburgh; Simon Finfer; Rinaldo Bellomo; Laurent Billot; Alan Cass; David Gattas; Parisa Glass; Jeffrey Lipman; Bette Liu; Colin McArthur; Shay McGuinness; Dorrilyn Rajbhandari; Colman B Taylor; Steven A R Webb
Journal:  N Engl J Med       Date:  2012-10-17       Impact factor: 91.245

9.  Intensive insulin therapy and pentastarch resuscitation in severe sepsis.

Authors:  Frank M Brunkhorst; Christoph Engel; Frank Bloos; Andreas Meier-Hellmann; Max Ragaller; Norbert Weiler; Onnen Moerer; Matthias Gruendling; Michael Oppert; Stefan Grond; Derk Olthoff; Ulrich Jaschinski; Stefan John; Rolf Rossaint; Tobias Welte; Martin Schaefer; Peter Kern; Evelyn Kuhnt; Michael Kiehntopf; Christiane Hartog; Charles Natanson; Markus Loeffler; Konrad Reinhart
Journal:  N Engl J Med       Date:  2008-01-10       Impact factor: 91.245

10.  Hydroxyethylstarch impairs renal function and induces interstitial proliferation, macrophage infiltration and tubular damage in an isolated renal perfusion model.

Authors:  Lars Hüter; Tim-Philipp Simon; Lenard Weinmann; Tobias Schuerholz; Konrad Reinhart; Gunter Wolf; Kerstin Ute Amann; Gernot Marx
Journal:  Crit Care       Date:  2009-02-25       Impact factor: 9.097

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