Literature DB >> 25534550

The role of concentration--effect relationships in the QTc interval prolongation: case sotalol.

Pertti J Neuvonen1, Erkki Elonen2.   

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Year:  2015        PMID: 25534550      PMCID: PMC4456139          DOI: 10.1111/bcp.12574

Source DB:  PubMed          Journal:  Br J Clin Pharmacol        ISSN: 0306-5251            Impact factor:   4.335


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  9 in total

1.  Cardiac safety, drug-induced QT prolongation and torsade de pointes (TdP).

Authors:  James M Ritter
Journal:  Br J Clin Pharmacol       Date:  2012-03       Impact factor: 4.335

2.  Drug-induced long QT syndrome and drug development.

Authors:  J M Ritter
Journal:  Br J Clin Pharmacol       Date:  2008-09       Impact factor: 4.335

3.  Sotalol intoxication with prolonged Q-T interval and severe tachyarrhythmias.

Authors:  E Elonen; P J Neuvonen; L Tarssanen; R Kala
Journal:  Br Med J       Date:  1979-05-05

4.  Sotalol: a new, safe beta adrenergic receptor blocking agent.

Authors:  W S Frankl; L A Soloff
Journal:  Am J Cardiol       Date:  1968-08       Impact factor: 2.778

5.  Prolongation of the Q-T interval caused by sotalol--possible association with ventricular tachyarrhythmias.

Authors:  M Laakso; P J Pentikäinen; K Pyörälä; P J Neuvonen
Journal:  Eur Heart J       Date:  1981-08       Impact factor: 29.983

6.  Prolonged Q-T interval and severe tachyarrhythmias, common features of sotalol intoxication.

Authors:  P J Neuvonen; E Elonen; T Vuorenmaa; M Laakso
Journal:  Eur J Clin Pharmacol       Date:  1981       Impact factor: 2.953

Review 7.  The role of concentration-effect relationships in the assessment of QTc interval prolongation.

Authors:  Nicholas P France; Oscar Della Pasqua
Journal:  Br J Clin Pharmacol       Date:  2015-01       Impact factor: 4.335

8.  Sotalol prolongation of the QTc interval in hypertensive patients.

Authors:  P J Neuvonen; E Elonen; A Tanskanen; J Tuomilehto
Journal:  Clin Pharmacol Ther       Date:  1982-07       Impact factor: 6.875

9.  Sotalol intoxication, two patients with concentration-effect relationships.

Authors:  P J Neuvonen; E Elonen; L Tarssanen
Journal:  Acta Pharmacol Toxicol (Copenh)       Date:  1979-07
  9 in total
  1 in total

1.  On the role of concentration-effect relationships in safety pharmacology: only the dose makes a drug not to be poison!

Authors:  Oscar Della Pasqua
Journal:  Br J Clin Pharmacol       Date:  2015-06       Impact factor: 4.335

  1 in total

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