Literature DB >> 2553415

"False positive" immunoscintigraphic diagnosis of liver abscesses in a patient with a necrotic liver tumour.

T Leitha1, A Stümpflen, A Gebauer, G Amann, R Dudczak.   

Abstract

The following report describes the scintigraphic findings in a patient who underwent immunoscintigraphy with anti granulocyte Mab because of septic fever. Focal tracer accumulation in the liver corresponding with hypoechoic and hypodense areas documented by sonography and computed tomography was believed to represent liver abscesses, yet surgery and autopsy revealed a large necrotic cholangiocellular liver carcinoma. The possible mechanisms, which had led to the false positive immunoscintigraphic image are discussed and we conclude that a necrotic neoplasm has to be a major differential diagnosis in any case of positive liver uptake in an anti granulocyte scan.

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Year:  1989        PMID： 2553415     DOI： 10.1007/BF00251683

Source DB:  PubMed          Journal:  Eur J Nucl Med        ISSN： 0340-6997


  10 in total

1.  Immunoscintigraphic localization of inflammatory lesions: concept, radiolabelling and in vitro testing of a granulocyte specific antibody.

Authors:  R Y Andres; P A Schubiger; L Tiefenauer; K Seybold; J T Locher; J P Mach; F Buchegger
Journal:  Eur J Nucl Med       Date:  1988

2.  Unsuspected extra-abdominal sites of infection: scintigraphic detection with indium-111-labeled leukocytes.

Authors:  J E Seabold; D G Wilson; L M Lieberman; C M Boyd
Journal:  Radiology       Date:  1984-04       Impact factor: 11.105

3.  Positive indium-111 leukocyte scintigraphy in a skeletal metastasis.

Authors:  G N Sfakianakis; W Mnaymneh; L Ghandur-Mnaymneh; W Al-Sheikh; M Hourani; A Heal
Journal:  AJR Am J Roentgenol       Date:  1982-09       Impact factor: 3.959

4.  Monoclonal antibodies identify a CEA crossreacting antigen of 95 kD (NCA-95) distinct in antigenicity and tissue distribution from the previously described NCA of 55 kD.

Authors:  F Buchegger; M Schreyer; S Carrel; J P Mach
Journal:  Int J Cancer       Date:  1984-05-15       Impact factor: 7.396

5.  Immunohistochemical localization and molecular characteristics of three monoclonal antibody-defined epitopes detectable on carcinoembryonic antigen (CEA).

Authors:  K Bosslet; G Lüben; A Schwarz; E Hundt; H P Harthus; F R Seiler; C Muhrer; G Klöppel; K Kayser; H H Sedlacek
Journal:  Int J Cancer       Date:  1985-07-15       Impact factor: 7.396

6.  Differentiating hepatic abscess from tumor: combined 111In white blood cell and 99mTc liver scans.

Authors:  H D Fawcett; R L Lantieri; A Frankel; I R McDougall
Journal:  AJR Am J Roentgenol       Date:  1980-07       Impact factor: 3.959

7.  Immunoscintigraphic localization of inflammatory lesions: pharmacokinetics and estimated absorbed radiation dose in man.

Authors:  P H Hasler; K Seybold; R Y Andres; J T Locher; P A Schubiger
Journal:  Eur J Nucl Med       Date:  1988

8.  Possible pitfalls with clinical imaging of indium-111 leukocytes: concise communication.

Authors:  R E Coleman; D Welch
Journal:  J Nucl Med       Date:  1980-02       Impact factor: 10.057

9.  Imaging of inflammatory and infectious lesions after injection of radioiodinated monoclonal anti-granulocytes antibodies.

Authors:  J T Locher; K Seybold; R Y Andres; P A Schubiger; J P Mach; F Buchegger
Journal:  Nucl Med Commun       Date:  1986-09       Impact factor: 1.690

10.  Immunoscintigraphic localization of inflammatory lesions: clinical experience.

Authors:  K Seybold; J T Locher; C Coosemans; R Y Andres; P A Schubiger; P Bläuenstein
Journal:  Eur J Nucl Med       Date:  1988
  10 in total

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