Literature DB >> 25533675

Modelling bladder cancer in mice: opportunities and challenges.

Takashi Kobayashi1, Tomasz B Owczarek2, James M McKiernan3, Cory Abate-Shen4.   

Abstract

The prognosis and treatment of bladder cancer have improved little in the past 20 years. Bladder cancer remains a debilitating and often fatal disease, and is among the most costly cancers to treat. The generation of informative mouse models has the potential to improve our understanding of bladder cancer progression, as well as to affect its diagnosis and treatment. However, relatively few mouse models of bladder cancer have been described, and in particular, few that develop invasive cancer phenotypes. This Review focuses on opportunities for improving the landscape of mouse models of bladder cancer.

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Year:  2015        PMID： 25533675      PMCID： PMC4386904          DOI： 10.1038/nrc3858

Source DB:  PubMed          Journal:  Nat Rev Cancer        ISSN： 1474-175X            Impact factor:   60.716


  160 in total

Review 1.  The androgen receptor and stem cell pathways in prostate and bladder cancers (review).

Authors:  Katarzyna Marcinkiewicz; Kymora B Scotland; Stephen A Boorjian; Emeli M Nilsson; Jenny Liao Persson; Per Anders Abrahamsson; Cinzia Allegrucci; Ieuan A Hughes; Lorraine J Gudas; Nigel P Mongan
Journal:  Int J Oncol       Date:  2011-09-28       Impact factor: 5.650

Review 2.  How genetically engineered mouse tumor models provide insights into human cancers.

Authors:  Katerina Politi; William Pao
Journal:  J Clin Oncol       Date:  2011-01-24       Impact factor: 44.544

3.  Differential expression of cell cycle regulators in phenotypic variants of transgenically induced bladder tumors: implications for tumor behavior.

Authors:  Antonio Garcia-España; Edgard Salazar; Tung-Tien Sun; Xue-Ru Wu; Angel Pellicer
Journal:  Cancer Res       Date:  2005-02-15       Impact factor: 12.701

4.  A population of progenitor cells in the basal and intermediate layers of the murine bladder urothelium contributes to urothelial development and regeneration.

Authors:  Sara A Colopy; Dale E Bjorling; William A Mulligan; Wade Bushman
Journal:  Dev Dyn       Date:  2014-05-19       Impact factor: 3.780

5.  Loss of p53 and acquisition of angiogenic microRNA profile are insufficient to facilitate progression of bladder urothelial carcinoma in situ to invasive carcinoma.

Authors:  Francisco Ayala de la Peña; Keizo Kanasaki; Megumi Kanasaki; Neelima Tangirala; Genta Maeda; Raghu Kalluri
Journal:  J Biol Chem       Date:  2011-03-09       Impact factor: 5.157

Review 6.  Intrinsic basal and luminal subtypes of muscle-invasive bladder cancer.

Authors:  Woonyoung Choi; Bogdan Czerniak; Andrea Ochoa; Xiaoping Su; Arlene Siefker-Radtke; Colin Dinney; David J McConkey
Journal:  Nat Rev Urol       Date:  2014-06-24       Impact factor: 14.432

Review 7.  Importance of orthotopic transplantation procedures in assessing the effects of transfected genes on human tumor growth and metastasis.

Authors:  R S Kerbel; I Cornil; D Theodorescu
Journal:  Cancer Metastasis Rev       Date:  1991-10       Impact factor: 9.264

8.  Bone morphogenetic protein 4 signaling regulates epithelial renewal in the urinary tract in response to uropathogenic infection.

Authors:  Indira U Mysorekar; Megan Isaacson-Schmid; Jennifer N Walker; Jason C Mills; Scott J Hultgren
Journal:  Cell Host Microbe       Date:  2009-05-08       Impact factor: 21.023

9.  Bladder cancers arise from distinct urothelial sub-populations.

Authors:  Jason Van Batavia; Tammer Yamany; Andrei Molotkov; Hanbin Dan; Mahesh Mansukhani; Ekaterina Batourina; Kerry Schneider; Daniel Oyon; Mark Dunlop; Xue-Ru Wu; Carlos Cordon-Cardo; Cathy Mendelsohn
Journal:  Nat Cell Biol       Date:  2014-09-14       Impact factor: 28.824

10.  Lkb1 and Pten synergise to suppress mTOR-mediated tumorigenesis and epithelial-mesenchymal transition in the mouse bladder.

Authors:  Boris Y Shorning; David Griffiths; Alan R Clarke
Journal:  PLoS One       Date:  2011-01-19       Impact factor: 3.240
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  56 in total

1.  Histone demethylase JMJD1A promotes urinary bladder cancer progression by enhancing glycolysis through coactivation of hypoxia inducible factor 1α.

Authors:  W Wan; K Peng; M Li; L Qin; Z Tong; J Yan; B Shen; C Yu
Journal:  Oncogene       Date:  2017-03-06       Impact factor: 9.867

2.  Establishing and characterization of human and murine bladder cancer organoids.

Authors:  Neveen Said
Journal:  Transl Androl Urol       Date:  2019-07

Review 3.  Patient-derived xenografts as in vivo models for research in urological malignancies.

Authors:  Takahiro Inoue; Naoki Terada; Takashi Kobayashi; Osamu Ogawa
Journal:  Nat Rev Urol       Date:  2017-02-21       Impact factor: 14.432

Review 4.  Urothelial generation and regeneration in development, injury, and cancer.

Authors:  Caihong Wang; Whitney Trotter Ross; Indira U Mysorekar
Journal:  Dev Dyn       Date:  2017-03-02       Impact factor: 3.780

Review 5.  Optimizing mouse models for precision cancer prevention.

Authors:  Clémentine Le Magnen; Aditya Dutta; Cory Abate-Shen
Journal:  Nat Rev Cancer       Date:  2016-02-19       Impact factor: 60.716

6.  Molecular Subtype-Specific Immunocompetent Models of High-Grade Urothelial Carcinoma Reveal Differential Neoantigen Expression and Response to Immunotherapy.

Authors:  Ryoichi Saito; Christof C Smith; Takanobu Utsumi; Lisa M Bixby; Jordan Kardos; Sara E Wobker; Kyle G Stewart; Shengjie Chai; Ujjawal Manocha; Kevin M Byrd; Jeffrey S Damrauer; Scott E Williams; Benjamin G Vincent; William Y Kim
Journal:  Cancer Res       Date:  2018-05-21       Impact factor: 12.701

7.  A predictive nomogram for individualized recurrence stratification of bladder cancer using multiparametric MRI and clinical risk factors.

Authors:  Xiaopan Xu; Huanjun Wang; Peng Du; Fan Zhang; Shurong Li; Zhongwei Zhang; Jing Yuan; Zhengrong Liang; Xi Zhang; Yan Guo; Yang Liu; Hongbing Lu
Journal:  J Magn Reson Imaging       Date:  2019-04-13       Impact factor: 4.813

Review 8.  Preclinical mouse solid tumour models: status quo, challenges and perspectives.

Authors:  Nicolas Gengenbacher; Mahak Singhal; Hellmut G Augustin
Journal:  Nat Rev Cancer       Date:  2017-10-27       Impact factor: 60.716

Review 9.  Contrast effects of autophagy in the treatment of bladder cancer.

Authors:  Ece Konac; Yener Kurman; Sümer Baltaci
Journal:  Exp Biol Med (Maywood)       Date:  2020-09-20

10.  Perspective: Humanized Pig Models of Bladder Cancer.

Authors:  Natália Vieira Segatto; Camila Bonemann Bender; Fabiana Kommling Seixas; Kyle Schachtschneider; Lawrence Schook; Noah Robertson; Aisha Qazi; Maximillian Carlino; Luke Jordan; Courtni Bolt; Tiago Collares
Journal:  Front Mol Biosci       Date:  2021-05-17
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