Jonathan C Park1, Nabil E Habib2, Roy M Moate2. 1. From the Royal Eye Infirmary (Park, Habib), the Peninsula Medical School (Habib), and Plymouth Electron Microscope Centre (Moate), University of Plymouth, Plymouth, United Kingdom. Electronic address: jonpark777@gmail.com. 2. From the Royal Eye Infirmary (Park, Habib), the Peninsula Medical School (Habib), and Plymouth Electron Microscope Centre (Moate), University of Plymouth, Plymouth, United Kingdom.
Abstract
PURPOSE: To assess a newly recognized long-term complication of Descemet-stripping automated endothelial keratoplasty (DSAEK). SETTING: Plymouth Royal Eye Infirmary and Plymouth Electron Microscope Centre, Plymouth, United Kingdom. DESIGN: Retrospective case series. METHODS: This study evaluated cases of intraocular lens (IOL) opacification that developed after uneventful DSAEK. None of the IOLs was previously known to opacify. In 1 case, the opacified IOL was explanted and analyzed using detailed light microscopy, scanning electron microscopic (SEM) analysis, and element x-ray spectroscopy. RESULTS: In all 5 cases, the IOL was hydrophilic acrylic and the eye developed IOL anterior surface opacification 4 to 12 months after DSAEK. In 1 eye, the opacification was symptomatic; thus, an IOL exchange was performed. Light microscopy and SEM analysis of the explanted IOL confirmed opacification on the anterior surface and subsurface areas. X-ray element spectroscopy showed the granules were composed of calcium and phosphorous. CONCLUSIONS: These cases indicate that IOL opacification after DSAEK is a late, although newly recognized, complication of endothelial keratoplasty. FINANCIAL DISCLOSURE: No author has a financial or proprietary interest in any material or method mentioned.
PURPOSE: To assess a newly recognized long-term complication of Descemet-stripping automated endothelial keratoplasty (DSAEK). SETTING: Plymouth Royal Eye Infirmary and Plymouth Electron Microscope Centre, Plymouth, United Kingdom. DESIGN: Retrospective case series. METHODS: This study evaluated cases of intraocular lens (IOL) opacification that developed after uneventful DSAEK. None of the IOLs was previously known to opacify. In 1 case, the opacified IOL was explanted and analyzed using detailed light microscopy, scanning electron microscopic (SEM) analysis, and element x-ray spectroscopy. RESULTS: In all 5 cases, the IOL was hydrophilic acrylic and the eye developed IOL anterior surface opacification 4 to 12 months after DSAEK. In 1 eye, the opacification was symptomatic; thus, an IOL exchange was performed. Light microscopy and SEM analysis of the explanted IOL confirmed opacification on the anterior surface and subsurface areas. X-ray element spectroscopy showed the granules were composed of calcium and phosphorous. CONCLUSIONS: These cases indicate that IOL opacification after DSAEK is a late, although newly recognized, complication of endothelial keratoplasty. FINANCIAL DISCLOSURE: No author has a financial or proprietary interest in any material or method mentioned.
Authors: Simon S M Fung; Evripidis Sykakis; Niaz M Islam; Hadi J Zambarakji; Ramin Khoramnia; Gerd U Auffarth; Dipak N Parmar Journal: J Ophthalmol Date: 2015-03-18 Impact factor: 1.909
Authors: Arie L Marcovich; Tamer Tandogan; Mor Bareket; Eva Eting; Ifat Kaplan-Ashiri; Amir Bukelman; Gerd U Auffarth; Ramin Khoramnia Journal: BMJ Open Ophthalmol Date: 2018-12-15