Literature DB >> 25532378

[Analysis of traditional Chinese medicine syndrome, traditional Chinese medicine and western medicine in 84 697 patients with coronary heart disease based on big data].

Gui-hua Li, Hong-yan Jiang, Yan-ming Xie, Jun-jie Jiang, Wei Yang, Wei Zhao, Yan Zhuang, Yong-yan Wang.   

Abstract

In order to understand the clinical characteristics of patients with coronary heart disease (CHD) in real world and provide reference for clinical prevention and treatment, this study analyzed informations of patient with CHD in hospital information system. Data from 17 national hospitals were collected. Select patients with coronaryheart disease in diagnosis of the first place in 17 hospitals, general informations and traditional Chinese medicine (TCM) syndrome, complications, medicine were analyzed using frequency method and association rules. This study included 84 697 patients with CHD, the majority of men and in the elderly. The average age of patients was 71 years. The proportion of men to women was about 1. 45: 1. Hospital stay time ranged from 8 to 14 d. The most common total hospitalization cost distribution was 5 000-20 000 RMB. Young patients have a rising trend year by year. The death of patients increased with increasing age. Common complications were hypertension, diabetes, cerebral infarction and hyperlipidemia, 57.24 percent of the CHD patient complicated with hypertension, 21.94 percent patients complicated with diabetes. Among TCM syndrome types, Qi-Yin deficiency and qi deficiency blood stasis were the most common syndromes. Blood stasis was the highest syndrome elements, accounted for 79.97%, followed by Qi deficiency, phlegm, Yin deficiency, and so on. The most common western medicine was aspirin, followed with isosorbide dinitrate, clopidogrel. The most common used traditional Chinese medicine was danhong injection, followed by shuxuetong injection. Combined with removing blood stasis drugs has been more common at present clinical treatment, there were 43.46 percent of patients combined with anti-platelet western drug and injection of removing blood stasis.

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Year:  2014        PMID: 25532378

Source DB:  PubMed          Journal:  Zhongguo Zhong Yao Za Zhi        ISSN: 1001-5302


  5 in total

1.  Comparison of the Pharmacokinetic Profiles of Ceftriaxone Used Alone and Combined with Danhong Injection in Old Rats.

Authors:  Qian Zhang; Jianming Guo; Guoliang Dai; Jianping Li; Lijing Zhu; Shufen He; Yang Zong; Zhishu Tang; Buchang Zhao; Wenzheng Ju; Jinao Duan
Journal:  Eur J Drug Metab Pharmacokinet       Date:  2019-08       Impact factor: 2.441

2.  Danhong Injection Price Trend and Its Utilization by Coronary Heart Disease Patients: Evidence From Hospital Records in China.

Authors:  Liming Liu; Yue Xu; Zihan Su; Xiaowei Man; Yan Jiang; Liying Zhao; Wei Cheng
Journal:  Front Pharmacol       Date:  2022-05-04       Impact factor: 5.988

3.  Integrated Modules Analysis to Explore the Molecular Mechanisms of Phlegm-Stasis Cementation Syndrome with Ischemic Heart Disease.

Authors:  Wei-Ming Xu; Kuo Yang; Li-Jie Jiang; Jing-Qing Hu; Xue-Zhong Zhou
Journal:  Front Physiol       Date:  2018-01-22       Impact factor: 4.566

4.  Cost-consequence analysis of salvianolate injection for the treatment of coronary heart disease.

Authors:  Pengxin Dong; Hao Hu; Xiaodong Guan; Carolina Oi Lam Ung; Luwen Shi; Sheng Han; Shuwen Yu
Journal:  Chin Med       Date:  2018-06-14       Impact factor: 5.455

5.  Development of a Diagnostic Questionnaire for Damp Phlegm Pattern and Blood Stasis Pattern in Coronary Heart Disease Patients (CHD-DPBSPQ).

Authors:  Ge Fang; Ling-Lin Zhang; Qi Ren; Xiao-Wen Zhou; Bin Wang; Xuan Zhou; Xiao-Qi Liu; Dan-Hong Peng; Xin-Lin Chen; Xian-Tao Li
Journal:  Evid Based Complement Alternat Med       Date:  2019-11-26       Impact factor: 2.629

  5 in total

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