BACKGROUND: Epidemiological studies evaluating the association between vitamin E intake and glioma risk have produced inconsistent results. Thus, we conducted a meta-analysis to summarize the evidence from epidemiological studies of vitamin E intake with the risk of glioma. METHODS: Pertinent studies were identified by a search in pubmed and web of knowledge up to August 2014. The random-effect model was used to combine the results. Publication bias was estimated using the Egger's regression asymmetry test. RESULTS: Twelve studies including 3180 glioma cases about vitamin E intake with the risk of glioma were included in this meta-analysis. The combined relative risk (RR) of glioma associated with vitamin E intake was 0.88 (95% CI = 0.69-1.12). The association was significant neither in the case-control studies nor in the cohort studies. No publication biases were found. CONCLUSIONS: Our analysis indicated that vitamin E intake is not associated with the risk of glioma.
BACKGROUND: Epidemiological studies evaluating the association between vitamin E intake and glioma risk have produced inconsistent results. Thus, we conducted a meta-analysis to summarize the evidence from epidemiological studies of vitamin E intake with the risk of glioma. METHODS: Pertinent studies were identified by a search in pubmed and web of knowledge up to August 2014. The random-effect model was used to combine the results. Publication bias was estimated using the Egger's regression asymmetry test. RESULTS: Twelve studies including 3180 glioma cases about vitamin E intake with the risk of glioma were included in this meta-analysis. The combined relative risk (RR) of glioma associated with vitamin E intake was 0.88 (95% CI = 0.69-1.12). The association was significant neither in the case-control studies nor in the cohort studies. No publication biases were found. CONCLUSIONS: Our analysis indicated that vitamin E intake is not associated with the risk of glioma.
Authors: Kathleen M Egan; Stephanie A Smith-Warner; Yiyang Yue; Jordan H Creed; David J Cote; Meir J Stampfer; Molin Wang; Øivind Midttun; Adrian McCann; Per Magne Ueland; Jeremy Furtado Journal: Sci Rep Date: 2021-04-29 Impact factor: 4.379
Authors: Charlie N Saunders; Alex J Cornish; Ben Kinnersley; Philip J Law; Elizabeth B Claus; Dora Il'yasova; Joellen Schildkraut; Jill S Barnholtz-Sloan; Sara H Olson; Jonine L Bernstein; Rose K Lai; Stephen Chanock; Preetha Rajaraman; Christoffer Johansen; Robert B Jenkins; Beatrice S Melin; Margaret R Wrensch; Marc Sanson; Melissa L Bondy; Richard S Houlston Journal: Neuro Oncol Date: 2020-02-20 Impact factor: 12.300
Authors: Charlie N Saunders; Alex J Cornish; Ben Kinnersley; Philip J Law; Richard S Houlston Journal: Br J Cancer Date: 2020-10-06 Impact factor: 7.640