| Literature DB >> 2553152 |
E V Komissarova, S M Tolpygo, Iu V Polyntsev, Iu V Krizhevskaia, P A Shestakov, A V Kotov, O A Gomazkov.
Abstract
Angiotensin-converting enzyme (ACE) activity in serum and some brain areas, level of angiotensin I in the blood and drinking behaviour during immunization of rats against conjugate of angiotensin II with bovine serum albumin (BSA) were studied. The results show that an increase in antibodies against angiotensin II was correlated with elevated ACE activity in serum. There was a distinct tendency towards elevated level of angiotensin I in the blood. After a 6 month's immunization ACE-activity was reduced twofold to threefold in midbrain and hypothalamus-thalamus. During immunization water-uptake was increased by 40-45%.Entities:
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Year: 1989 PMID： 2553152
Source DB: PubMed Journal: Biull Eksp Biol Med ISSN： 0365-9615