Literature DB >> 25530491

Mitochondrial changes in endometrial carcinoma: possible role in tumor diagnosis and prognosis (review).

Antonella Cormio1, Gennaro Cormio2, Clara Musicco3, Anna Maria Sardanelli4, Giuseppe Gasparre5, Maria Nicola Gadaleta3.   

Abstract

Endometrial carcinoma (EC) is a solid neoplasia for which a role for mitochondria in cancer progression is currently emerging and yet represents a diagnostic and prognostic challenge. EC is one of the most frequently occurring gynecological malignancies in the Western world whose incidence has increased significantly during the last decades. Here, we review the literature data on mitochondrial changes reported in EC, namely, mitochondrial DNA (mtDNA) mutations, increase in mitochondrial biogenesis and discuss whether they may be used as new cancer biomarkers for early detection and prognosis of this cancer.

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Year:  2014        PMID： 25530491     DOI： 10.3892/or.2014.3690

Source DB:  PubMed          Journal:  Oncol Rep        ISSN： 1021-335X            Impact factor:   3.906


  8 in total

1.  Olive oil exhibits osteoprotection in ovariectomized rats without estrogenic effects.

Authors:  Xiaohua Zheng; Huijuan Huang; Xiaobing Zheng; Baoheng Li
Journal:  Exp Ther Med       Date:  2016-03-10       Impact factor: 2.447

2.  PGC1α and VDAC1 expression in endometrial cancer.

Authors:  Ofra Castro Wersäll; Lina Löfstedt; Igor Govorov; Miriam Mints; Marike Gabrielson; Maria Shoshan
Journal:  Mol Clin Oncol       Date:  2020-12-30

Review 3.  Exosomes as Theranostic Targets: Implications for the Clinical Prognosis of Aggressive Cancers.

Authors:  Richa Gulati; Dhruva Nandi; Koustav Sarkar; P Venkataraman; K M Ramkumar; Priya Ranjan; Rajiv Janardhanan
Journal:  Front Mol Biosci       Date:  2022-06-23

4.  Mitochondrial supercomplex assembly promotes breast and endometrial tumorigenesis by metabolic alterations and enhanced hypoxia tolerance.

Authors:  Kazuhiro Ikeda; Kuniko Horie-Inoue; Takashi Suzuki; Rutsuko Hobo; Norie Nakasato; Satoru Takeda; Satoshi Inoue
Journal:  Nat Commun       Date:  2019-09-11       Impact factor: 14.919

5.  TIMM8A is associated with dysfunction of immune cell in BRCA and UCEC for predicting anti-PD-L1 therapy efficacy.

Authors:  Xiaoyu Zhu; Zile Yuan; Sheng Cheng; Hongyi Wang; Yuxuan Liao; Dawei Zhou; Zhiqiang Wu
Journal:  World J Surg Oncol       Date:  2022-10-07       Impact factor: 3.253

6.  Packaging and transfer of mitochondrial DNA via exosomes regulate escape from dormancy in hormonal therapy-resistant breast cancer.

Authors:  Pasquale Sansone; Claudia Savini; Ivana Kurelac; Qing Chang; Laura Benedetta Amato; Antonio Strillacci; Anna Stepanova; Luisa Iommarini; Chiara Mastroleo; Laura Daly; Alexander Galkin; Basant Kumar Thakur; Nadine Soplop; Kunihiro Uryu; Ayuko Hoshino; Larry Norton; Massimiliano Bonafé; Monica Cricca; Giuseppe Gasparre; David Lyden; Jacqueline Bromberg
Journal:  Proc Natl Acad Sci U S A       Date:  2017-10-11       Impact factor: 11.205

7.  SPARC Inhibits Metabolic Plasticity in Ovarian Cancer.

Authors:  Christine Naczki; Bincy John; Chirayu Patel; Ashlyn Lafferty; Alia Ghoneum; Hesham Afify; Michael White; Amanda Davis; Guangxu Jin; Steven Kridel; Neveen Said
Journal:  Cancers (Basel)       Date:  2018-10-16       Impact factor: 6.639

Review 8.  Mitochondrial Dysfunctions in Type I Endometrial Carcinoma: Exploring Their Role in Oncogenesis and Tumor Progression.

Authors:  Clara Musicco; Gennaro Cormio; Vito Pesce; Vera Loizzi; Ettore Cicinelli; Leonardo Resta; Girolamo Ranieri; Antonella Cormio
Journal:  Int J Mol Sci       Date:  2018-07-17       Impact factor: 5.923
  8 in total

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