| Literature DB >> 2553022 |
G Gauquelin1, G Thibault, R Garcia.
Abstract
Specific receptors for Endothelin (Et) have been identified in the glomerulus of rat kidney. Human 125I-ET binds to a single population of high affinity receptors in glomerular membranes from normal rats with a mean equilibrium dissociation constant of 200 pM. The binding was time and temperature-dependent, saturable and reversible. The Et-receptor complex was not affected by either vasopressin, atrial natriuretic factor or angiotension II.Entities:
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Year: 1989 PMID： 2553022 DOI： 10.1016/0006-291x(89)91681-1
Source DB: PubMed Journal: Biochem Biophys Res Commun ISSN： 0006-291X Impact factor: 3.575