Literature DB >> 25530033

Reporting of embryo transfer methods in IVF research: a cross-sectional study.

Pietro Gambadauro1, Ramesan Navaratnarajah2.   

Abstract

The reporting of embryo transfer methods in IVF research was assessed through a cross-sectional analysis of randomized controlled trials (RCTs) published between 2010 and 2011. A systematic search identified 325 abstracts; 122 RCTs were included in the study. Embryo transfer methods were described in 42 out of 122 articles (34%). Catheters (32/42 [76%]) or ultrasound guidance (31/42 [74%]) were most frequently mentioned. Performer 'blinding' (12%) or technique standardization (7%) were seldom reported. The description of embryo transfer methods was significantly more common in trials published by journals with lower impact factor (less than 3, 39.6%; 3 or greater, 21.5%; P = 0.037). Embryo transfer methods were reported more often in trials with pregnancy as the main end-point (33% versus 16%) or with positive outcomes (37.8% versus 25.0%), albeit not significantly. Multivariate logistic regression confirmed that RCTs published in higher impact factor journals are less likely to describe embryo transfer methods (OR 0.371; 95% CI 0.143 to 0.964). Registered trials, trials conducted in an academic setting, multi-centric studies or full-length articles were not positively associated with embryo transfer methods reporting rate. Recent reports of randomized IVF trials rarely describe embryo transfer methods. The under-reporting of research methods might compromise reproducibility and suitability for meta-analysis.
Copyright © 2014 Reproductive Healthcare Ltd. Published by Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  embryo transfer; in-vitro fertilization; randomized controlled trials; reproducibility of research; research methods; risk of bias

Mesh:

Year:  2014        PMID: 25530033     DOI: 10.1016/j.rbmo.2014.10.013

Source DB:  PubMed          Journal:  Reprod Biomed Online        ISSN: 1472-6483            Impact factor:   3.828


  2 in total

1.  Low versus high volume of culture medium during embryo transfer: a randomized clinical trial.

Authors:  George Α Sigalos; Yannis Michalopoulos; Athanasios G Kastoras; Olga Triantafyllidou; Nikos F Vlahos
Journal:  J Assist Reprod Genet       Date:  2017-12-12       Impact factor: 3.412

2.  National Survey Highlights the Urgent Need for Standardisation of Embryo Transfer Techniques in the UK.

Authors:  Lewis Nancarrow; Nicola Tempest; Andrew J Drakeley; Roy Homburg; Richard Russell; Dharani K Hapangama
Journal:  J Clin Med       Date:  2021-06-27       Impact factor: 4.241

  2 in total

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