Literature DB >> 25529935

Symptoms of hormonal therapy and social support: Is there a connection? Comparison of symptom severity, symptom interference and social support among breast cancer patients receiving and not receiving adjuvant hormonal treatment.

Lea Ochayon1, Rina Tunin2, Aviva Yoselis3, Ilana Kadmon2.   

Abstract

BACKGROUND: Although there has been a significant reduction in mortality, breast cancer is the most frequent cancer among women worldwide. This decline in mortality has created a significant survivor population that must manage the post curative treatment phase, in order to have an increased quality of life and well-being. This study examined the relationship between symptom interference and severity with the perception of social support in the lives of women receiving or not receiving, hormonal therapy after initial treatment. METHODS AND SAMPLE: Participants completed symptom severity and interference questionnaires, (MDASI and BCPT), a social support survey (MSPSS) and demographic and comorbidity questionnaires.
RESULTS: Of the 210 women participants, higher symptom severity correlated with unemployment, living alone or being religious. Participants who were currently taking hormonal treatment (n = 84), reported a significant negative correlation between symptom severity, measured by MDASI, and social support (p = 0.006). Consequently, as symptom severity increased, perceived social support decreased. In the BCPT assessment, decreased cognitive functioning (p < 0.05), pain (p < 0.05), bladder dysfunction (p = 0.001), and reduced self-image (p < 0.01) were significantly negatively correlated with social support for those participants currently taking hormonal therapy. Participants who had not previously received hormonal therapy (n = 64), cognitive dysfunction and bladder dysfunction were negatively correlated with social support. Women with preexisting heart or pulmonary dysfunction and arthritis reported statistically significant higher levels of symptom severity and decreased perceptions of social support.
CONCLUSIONS: Identifying socio-demographic variables and comorbidities that affect hormonal therapy symptom burden is essential for offering adequate support for breast cancer survivors.
Copyright © 2014 Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  Breast cancer; Hormonal treatment; Social support; Sociodemographic variables; Survivors; Symptom severity

Mesh:

Substances:

Year:  2014        PMID: 25529935     DOI: 10.1016/j.ejon.2014.11.003

Source DB:  PubMed          Journal:  Eur J Oncol Nurs        ISSN: 1462-3889            Impact factor:   2.398


  4 in total

1.  Phenotypic and Molecular Evidence Suggests That Decrements in Morning and Evening Energy Are Distinct but Related Symptoms.

Authors:  Bradley E Aouizerat; Anand Dhruva; Steven M Paul; Bruce A Cooper; Kord M Kober; Christine Miaskowski
Journal:  J Pain Symptom Manage       Date:  2015-05-29       Impact factor: 3.612

2.  Symptom Map of Endocrine Therapy for Breast Cancer: A Scoping Review.

Authors:  Yehui Zhu; Susan M Cohen; Margaret Q Rosenzweig; Catherine M Bender
Journal:  Cancer Nurs       Date:  2019 Sep/Oct       Impact factor: 2.592

3.  Personal and clinical social support and adherence to adjuvant endocrine therapy among hormone receptor-positive breast cancer patients in an integrated health care system.

Authors:  Candyce H Kroenke; Dawn L Hershman; Scarlett L Gomez; Sara R Adams; Elizabeth H Eldridge; Marilyn L Kwan; Isaac J Ergas; Ai Kubo; Lawrence H Kushi
Journal:  Breast Cancer Res Treat       Date:  2018-04-18       Impact factor: 4.872

4.  Hot flushes and sweating, sleep problems, joint and muscular discomfort, and physical and mental exhaustion in breast cancer survivors during the first 24 months of tamoxifen therapy: a prospective observational study.

Authors:  Sumi Sung; Yul Ha Min; Seul Ki Park; Sae Byul Lee
Journal:  Front Oncol       Date:  2022-08-02       Impact factor: 5.738

  4 in total

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