Literature DB >> 25529120

Tunable rigidity of (polymeric core)-(lipid shell) nanoparticles for regulated cellular uptake.

Jiashu Sun1, Lu Zhang, Jiuling Wang, Qiang Feng, Dingbin Liu, Qifang Yin, Dongyan Xu, Yujie Wei, Baoquan Ding, Xinghua Shi, Xingyu Jiang.   

Abstract

Core-shell nanoparticles (NPs) with lipid shells and varying water content and rigidity but with the same chemical composition, size, and surface properties are assembled using a microfluidic platform. Rigidity can dramatically alter the cellular uptake efficiency, with more-rigid NPs able to pass more easily through cell membranes. The mechanism accounting for this rigidity-dependent cellular uptake is revealed through atomistic-level simulations.
© 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Entities:  

Keywords:  biomedical applications; cellular uptake; core-shell nanoparticles; drug delivery; microfluidics

Mesh：

Substances：

Year:  2014        PMID： 25529120     DOI： 10.1002/adma.201404788

Source DB:  PubMed          Journal:  Adv Mater        ISSN： 0935-9648            Impact factor:   30.849


  54 in total

1.  Cell and nanoparticle transport in tumour microvasculature: the role of size, shape and surface functionality of nanoparticles.

Authors:  Ying Li; Yanping Lian; Lucy T Zhang; Saad M Aldousari; Hassan S Hedia; Saeed A Asiri; Wing Kam Liu
Journal:  Interface Focus       Date:  2016-02-06       Impact factor: 3.906

Review 2.  Diverse Applications of Nanomedicine.

Authors:  Beatriz Pelaz; Christoph Alexiou; Ramon A Alvarez-Puebla; Frauke Alves; Anne M Andrews; Sumaira Ashraf; Lajos P Balogh; Laura Ballerini; Alessandra Bestetti; Cornelia Brendel; Susanna Bosi; Monica Carril; Warren C W Chan; Chunying Chen; Xiaodong Chen; Xiaoyuan Chen; Zhen Cheng; Daxiang Cui; Jianzhong Du; Christian Dullin; Alberto Escudero; Neus Feliu; Mingyuan Gao; Michael George; Yury Gogotsi; Arnold Grünweller; Zhongwei Gu; Naomi J Halas; Norbert Hampp; Roland K Hartmann; Mark C Hersam; Patrick Hunziker; Ji Jian; Xingyu Jiang; Philipp Jungebluth; Pranav Kadhiresan; Kazunori Kataoka; Ali Khademhosseini; Jindřich Kopeček; Nicholas A Kotov; Harald F Krug; Dong Soo Lee; Claus-Michael Lehr; Kam W Leong; Xing-Jie Liang; Mei Ling Lim; Luis M Liz-Marzán; Xiaowei Ma; Paolo Macchiarini; Huan Meng; Helmuth Möhwald; Paul Mulvaney; Andre E Nel; Shuming Nie; Peter Nordlander; Teruo Okano; Jose Oliveira; Tai Hyun Park; Reginald M Penner; Maurizio Prato; Victor Puntes; Vincent M Rotello; Amila Samarakoon; Raymond E Schaak; Youqing Shen; Sebastian Sjöqvist; Andre G Skirtach; Mahmoud G Soliman; Molly M Stevens; Hsing-Wen Sung; Ben Zhong Tang; Rainer Tietze; Buddhisha N Udugama; J Scott VanEpps; Tanja Weil; Paul S Weiss; Itamar Willner; Yuzhou Wu; Lily Yang; Zhao Yue; Qian Zhang; Qiang Zhang; Xian-En Zhang; Yuliang Zhao; Xin Zhou; Wolfgang J Parak
Journal:  ACS Nano       Date:  2017-03-14       Impact factor: 15.881

3.  Physiologically Relevant Mechanics of Biodegradable Polyester Nanoparticles.

Authors:  Nourin Alsharif; Behnaz Eshaghi; Björn M Reinhard; Keith A Brown
Journal:  Nano Lett       Date:  2020-10-05       Impact factor: 11.189

4.  Polymeric Nanoparticles Controlled by On-Chip Self-Assembly Enhance Cancer Treatment Effectiveness.

Authors:  Sungjin Jung; Junseok Lee; Junha Lim; Jeeyeon Suh; Taeyoung Kim; Jungho Ahn; Won Jong Kim; YongTae Kim
Journal:  Adv Healthc Mater       Date:  2020-10-18       Impact factor: 9.933

5.  Multiple consecutive recapture of rigid nanoparticles using a solid-state nanopore sensor.

Authors:  Jung Soo Lee; Bin Peng; Ahmet C Sabuncu; Seungjin Nam; ChiWon Ahn; Moon J Kim; MinJun Kim
Journal:  Electrophoresis       Date:  2017-12-13       Impact factor: 3.535

6.  Therapeutic genome editing of triple-negative breast tumors using a noncationic and deformable nanolipogel.

Authors:  Peng Guo; Jiang Yang; Jing Huang; Debra T Auguste; Marsha A Moses
Journal:  Proc Natl Acad Sci U S A       Date:  2019-08-26       Impact factor: 11.205

Review 7.  Nanomedicine and Onco-Immunotherapy: From the Bench to Bedside to Biomarkers.

Authors:  Vanessa Acebes-Fernández; Alicia Landeria-Viñuela; Pablo Juanes-Velasco; Angela-Patricia Hernández; Andrea Otazo-Perez; Raúl Manzano-Román; Rafael Gongora; Manuel Fuentes
Journal:  Nanomaterials (Basel)       Date:  2020-06-29       Impact factor: 5.076

8.  Robust manufacturing of lipid-polymer nanoparticles through feedback control of parallelized swirling microvortices.

Authors:  Michael J Toth; Taeyoung Kim; YongTae Kim
Journal:  Lab Chip       Date:  2017-08-08       Impact factor: 6.799

Review 9.  Nanoplatforms for Targeted Stimuli-Responsive Drug Delivery: A Review of Platform Materials and Stimuli-Responsive Release and Targeting Mechanisms.

Authors:  Yuzhe Sun; Edward Davis
Journal:  Nanomaterials (Basel)       Date:  2021-03-16       Impact factor: 5.076

Review 10.  Physical Principles of Nanoparticle Cellular Endocytosis.

Authors:  Sulin Zhang; Huajian Gao; Gang Bao
Journal:  ACS Nano       Date:  2015-08-21       Impact factor: 15.881
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