Marc Barthet1, Kenneth F Binmoeller2, Geoffroy Vanbiervliet3, Jean-Michel Gonzalez1, Todd H Baron4, Stéphane Berdah1. 1. Faculty of Medicine, Aix-Marseille University, Marseille, France; Gastroenterology, Public Assistance Hospitals of Marseille, Marseille, France. 2. Interventional Endoscopy Services, California Pacific Medical Center, San Francisco, California, USA. 3. Faculty of Medicine, Aix-Marseille University, Marseille, France; Gastroenterology, University Hospital of Nice, Nice, France. 4. Division of Gastroenterology and Hepatology, University of North Carolina, Chapel Hill, North Carolina, USA.
Abstract
BACKGROUND: We established feasibility and safety for natural orifice transluminal endoscopic surgery (NOTES) GI anastomosis with a lumen-apposing stent in live pigs. This approach was performed in 3 patients. OBJECTIVE: Creation of a NOTES gastroduodenal anastomosis in patients. DESIGN: Case series. SETTING: Two tertiary-care referral centers at large academic hospitals in France and in the United States. PATIENTS: Patients with refractory benign duodenal stenosis and malignant duodenal obstruction. INTERVENTION: NOTES GI anastomosis with a lumen-apposing stent. MAIN OUTCOME MEASUREMENTS: Disappearence of gastric outlet obstruction. RESULTS: All 3 procedures were technically successful and uneventful, except 1 minor adverse event. There were no instances of stent occlusion or migration during follow-up. All patients resumed a normal diet. LIMITATIONS: Small case series. CONCLUSION: NOTES gastroenteric anastomosis is feasible and safe in humans. A prospective pilot study is warranted.
BACKGROUND: We established feasibility and safety for natural orifice transluminal endoscopic surgery (NOTES) GI anastomosis with a lumen-apposing stent in live pigs. This approach was performed in 3 patients. OBJECTIVE: Creation of a NOTES gastroduodenal anastomosis in patients. DESIGN: Case series. SETTING: Two tertiary-care referral centers at large academic hospitals in France and in the United States. PATIENTS: Patients with refractory benign duodenal stenosis and malignant duodenal obstruction. INTERVENTION: NOTES GI anastomosis with a lumen-apposing stent. MAIN OUTCOME MEASUREMENTS: Disappearence of gastric outlet obstruction. RESULTS: All 3 procedures were technically successful and uneventful, except 1 minor adverse event. There were no instances of stent occlusion or migration during follow-up. All patients resumed a normal diet. LIMITATIONS: Small case series. CONCLUSION: NOTES gastroenteric anastomosis is feasible and safe in humans. A prospective pilot study is warranted.
Authors: Rajesh Krishnamoorthi; Shivanand Bomman; Petros Benias; Richard A Kozarek; Joyce A Peetermans; Edmund McMullen; Ornela Gjata; Shayan S Irani Journal: Endosc Int Open Date: 2022-06-10
Authors: Adrian Culetto; Jean-Michel Gonzalez; Geoffroy Vanbiervliet; Pablo Miranda Garcia; Juan Ignacio Tellechea; Emmanuelle Garnier; Stephane Berdah; Marc Barthet Journal: Endosc Int Open Date: 2017-05-31
Authors: Amy Tyberg; Manuel Perez-Miranda; Ramon Sanchez-Ocaña; Irene Peñas; Carlos de la Serna; Janak Shah; Kenneth Binmoeller; Monica Gaidhane; Ian Grimm; Todd Baron; Michel Kahaleh Journal: Endosc Int Open Date: 2016-03