| Literature DB >> 25526302 |
Matthias Ernst1, Tracy Putoczki2.
Abstract
Although interleukin-17A (IL-17A) facilitates colon cancer development, its target cells remain elusive. In this issue of Immunity, Wang et al. (2014) now demonstrate that IL-17A receptors on the intestinal epithelium promote progression of APC mutant adenomas associated with IL-6 expression and that IL-17A confers chemotherapy resistance.Entities:
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Year: 2014 PMID: 25526302 DOI: 10.1016/j.immuni.2014.12.004
Source DB: PubMed Journal: Immunity ISSN: 1074-7613 Impact factor: 31.745