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Literature DB >> 25526298

Adding to the STING.

Abstract

STING (also known as MITA) is a central component in innate immunity against DNA virus. In this issue of Immunity, Wang et al. (2014) demonstrate that K27-linked polyubiquitination of STING (MITA) by the ER-associated E3 ligase AMFR is essential for STING (MITA)-mediated signaling and innate antiviral response.

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Year: 2014 PMID： 25526298 DOI： 10.1016/j.immuni.2014.12.002

Source DB: PubMed Journal: Immunity ISSN： 1074-7613 Impact factor: 31.745

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Cited

21 in total

Review 1. Self-regulation and cross-regulation of pattern-recognition receptor signalling in health and disease.

Authors: Xuetao Cao
Journal: Nat Rev Immunol Date: 2016-01 Impact factor: 53.106

Review 2. Multifaceted roles of TRIM38 in innate immune and inflammatory responses.

Authors: Ming-Ming Hu; Hong-Bing Shu
Journal: Cell Mol Immunol Date: 2017-02-13 Impact factor: 11.530

3. Human Cytomegalovirus DNA Polymerase Subunit UL44 Antagonizes Antiviral Immune Responses by Suppressing IRF3- and NF-κB-Mediated Transcription.

Authors: Yu-Zhi Fu; Shan Su; Hong-Mei Zou; Yi Guo; Su-Yun Wang; Shu Li; Min-Hua Luo; Yan-Yi Wang
Journal: J Virol Date: 2019-05-15 Impact factor: 5.103

Adding to the STING.

Review 1. Self-regulation and cross-regulation of pattern-recognition receptor signalling in health and disease.

Review 2. Multifaceted roles of TRIM38 in innate immune and inflammatory responses.

3. Human Cytomegalovirus DNA Polymerase Subunit UL44 Antagonizes Antiviral Immune Responses by Suppressing IRF3- and NF-κB-Mediated Transcription.

Review 4. Interaction Between Autophagy and Porphyromonas gingivalis-Induced Inflammation.

Review 5. The emerging roles of the STING adaptor protein in immunity and diseases.

6. iRhom2 is essential for innate immunity to DNA viruses by mediating trafficking and stability of the adaptor STING.

7. SENP7 Potentiates cGAS Activation by Relieving SUMO-Mediated Inhibition of Cytosolic DNA Sensing.

8. TRIM29 promotes DNA virus infections by inhibiting innate immune response.

9. Deubiquitinase USP35 restrains STING-mediated interferon signaling in ovarian cancer.

Review 10. Gp78 E3 Ubiquitin Ligase: Essential Functions and Contributions in Proteostasis.