Literature DB >> 25525984

What can we expect from biomarkers for acute kidney injury?

John A Kellum1, Prasad Devarajan.   

Abstract

Biomarkers for acute kidney injury have numerous potential roles to play both at the bedside and in the design and conduct of clinical trials. Given the heterogeneous nature of this disease and the difficulty, so far, in developing effective therapies, a strategy that deploys all of our available tools in the treatment and in study of treatments would seem prudent. In this review, we discuss how biomarkers will change the way we do we take care of patients with and do clinical trials in acute kidney injury and why, in fact, biomarkers are necessary.

Entities:  

Keywords:  acute kidney injury; acute renal failure; biomarkers; clinical trial design; diagnostics; risk assessment

Mesh:

Substances:

Year:  2014        PMID: 25525984      PMCID: PMC5672550          DOI: 10.2217/bmm.14.82

Source DB:  PubMed          Journal:  Biomark Med        ISSN: 1752-0363            Impact factor:   2.851


  23 in total

1.  Shp-1 mediates the antiproliferative activity of tissue inhibitor of metalloproteinase-2 in human microvascular endothelial cells.

Authors:  Dong-Wan Seo; Hongmei Li; Cheng-Kui Qu; Junseo Oh; Young-Sik Kim; Tere Diaz; Beiyang Wei; Jeung-Whan Han; William G Stetler-Stevenson
Journal:  J Biol Chem       Date:  2005-12-02       Impact factor: 5.157

2.  Incidence, outcomes, and comparisons across definitions of AKI in hospitalized individuals.

Authors:  Xiaoxi Zeng; Gearoid M McMahon; Steven M Brunelli; David W Bates; Sushrut S Waikar
Journal:  Clin J Am Soc Nephrol       Date:  2013-10-31       Impact factor: 8.237

Review 3.  KDOQI US commentary on the 2012 KDIGO clinical practice guideline for acute kidney injury.

Authors:  Paul M Palevsky; Kathleen D Liu; Patrick D Brophy; Lakhmir S Chawla; Chirag R Parikh; Charuhas V Thakar; Ashita J Tolwani; Sushrut S Waikar; Steven D Weisbord
Journal:  Am J Kidney Dis       Date:  2013-03-15       Impact factor: 8.860

Review 4.  Developing risk prediction models for kidney injury and assessing incremental value for novel biomarkers.

Authors:  Kathleen F Kerr; Allison Meisner; Heather Thiessen-Philbrook; Steven G Coca; Chirag R Parikh
Journal:  Clin J Am Soc Nephrol       Date:  2014-05-22       Impact factor: 8.237

5.  Diagnostic and prognostic stratification in the emergency department using urinary biomarkers of nephron damage: a multicenter prospective cohort study.

Authors:  Thomas L Nickolas; Kai M Schmidt-Ott; Pietro Canetta; Catherine Forster; Eugenia Singer; Meghan Sise; Antje Elger; Omar Maarouf; David Antonio Sola-Del Valle; Matthew O'Rourke; Evan Sherman; Peter Lee; Abdallah Geara; Philip Imus; Achuta Guddati; Allison Polland; Wasiq Rahman; Saban Elitok; Nasir Malik; James Giglio; Suzanne El-Sayegh; Prasad Devarajan; Sudarshan Hebbar; Subodh J Saggi; Barry Hahn; Ralph Kettritz; Friedrich C Luft; Jonathan Barasch
Journal:  J Am Coll Cardiol       Date:  2012-01-17       Impact factor: 24.094

6.  IGFBP-rP1 induces p21 expression through a p53-independent pathway, leading to cellular senescence of MCF-7 breast cancer cells.

Authors:  Shuguang Zuo; Chang Liu; Jianguo Wang; Fuqing Wang; Wanling Xu; Shao Cui; Lei Yuan; Xudong Chen; Wenjuan Fan; Mingchen Cui; Guohua Song
Journal:  J Cancer Res Clin Oncol       Date:  2012-03-06       Impact factor: 4.553

Review 7.  Neutrophil gelatinase-associated lipocalin as a biomarker of acute kidney injury: a critical evaluation of current status.

Authors:  Anja Haase-Fielitz; Michael Haase; Prasad Devarajan
Journal:  Ann Clin Biochem       Date:  2014-02-11       Impact factor: 2.057

8.  Acute Kidney Injury Network: report of an initiative to improve outcomes in acute kidney injury.

Authors:  Ravindra L Mehta; John A Kellum; Sudhir V Shah; Bruce A Molitoris; Claudio Ronco; David G Warnock; Adeera Levin
Journal:  Crit Care       Date:  2007       Impact factor: 9.097

9.  Discovery and validation of cell cycle arrest biomarkers in human acute kidney injury.

Authors:  Kianoush Kashani; Ali Al-Khafaji; Thomas Ardiles; Antonio Artigas; Sean M Bagshaw; Max Bell; Azra Bihorac; Robert Birkhahn; Cynthia M Cely; Lakhmir S Chawla; Danielle L Davison; Thorsten Feldkamp; Lui G Forni; Michelle Ng Gong; Kyle J Gunnerson; Michael Haase; James Hackett; Patrick M Honore; Eric A J Hoste; Olivier Joannes-Boyau; Michael Joannidis; Patrick Kim; Jay L Koyner; Daniel T Laskowitz; Matthew E Lissauer; Gernot Marx; Peter A McCullough; Scott Mullaney; Marlies Ostermann; Thomas Rimmelé; Nathan I Shapiro; Andrew D Shaw; Jing Shi; Amy M Sprague; Jean-Louis Vincent; Christophe Vinsonneau; Ludwig Wagner; Michael G Walker; R Gentry Wilkerson; Kai Zacharowski; John A Kellum
Journal:  Crit Care       Date:  2013-02-06       Impact factor: 9.097

10.  The urine output definition of acute kidney injury is too liberal.

Authors:  Azrina Md Ralib; John W Pickering; Geoffrey M Shaw; Zoltán H Endre
Journal:  Crit Care       Date:  2013-06-20       Impact factor: 9.097

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  8 in total

Review 1.  Diagnostic Criteria for Acute Kidney Injury: Present and Future.

Authors:  John A Kellum
Journal:  Crit Care Clin       Date:  2015-08-05       Impact factor: 3.598

2.  Does this patient have acute kidney injury? An AKI checklist.

Authors:  John A Kellum; Rinaldo Bellomo; Claudio Ronco
Journal:  Intensive Care Med       Date:  2015-08-20       Impact factor: 17.440

3.  Biomarker Enhanced Risk Prediction for Adverse Outcomes in Critically Ill Patients Receiving RRT.

Authors:  Francis Pike; Raghavan Murugan; Christopher Keener; Paul M Palevsky; Anitha Vijayan; Mark Unruh; Kevin Finkel; Xiaoyan Wen; John A Kellum
Journal:  Clin J Am Soc Nephrol       Date:  2015-06-05       Impact factor: 8.237

4.  Cross-species validation of cell cycle arrest markers for acute kidney injury in the rat during sepsis.

Authors:  Zhi-Yong Peng; Feihu Zhou; John A Kellum
Journal:  Intensive Care Med Exp       Date:  2016-05-31

Review 5.  Cell-cycle arrest and acute kidney injury: the light and the dark sides.

Authors:  John A Kellum; Lakhmir S Chawla
Journal:  Nephrol Dial Transplant       Date:  2015-06-04       Impact factor: 5.992

Review 6.  Biomarker-Guided Risk Assessment for Acute Kidney Injury: Time for Clinical Implementation?

Authors:  Christian Albert; Michael Haase; Annemarie Albert; Antonia Zapf; Rüdiger Christian Braun-Dullaeus; Anja Haase-Fielitz
Journal:  Ann Lab Med       Date:  2020-08-25       Impact factor: 3.464

7.  Urinary proteome of dogs with kidney injury during babesiosis.

Authors:  D Winiarczyk; K Michalak; L Adaszek; M Winiarczyk; S Winiarczyk
Journal:  BMC Vet Res       Date:  2019-12-04       Impact factor: 2.741

8.  Limiting Acute Kidney Injury Progression In Sepsis: Study Protocol and Trial Simulation.

Authors:  Luca Molinari; Fabienne Heskia; Sadudee Peerapornratana; Claudio Ronco; Louis Guzzi; Seth Toback; Robert Birch; Hadi Beyhaghi; Thomas Kwan; J Patrick Kampf; Donald M Yealy; John A Kellum
Journal:  Crit Care Med       Date:  2021-10-01       Impact factor: 9.296

  8 in total

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