| Literature DB >> 25525870 |
Costas A Lyssiotis1, Lewis C Cantley2.
Abstract
Cancer cells have distinctive nutrient demands to fuel growth and proliferation, including the disproportionate use of glucose, glutamine, and fatty acids. Comerford et al. and Mashimo et al. now demonstrate that several types of cancer are avid consumers of acetate, which facilitates macromolecular biosynthesis and histone modification.Entities:
Year: 2014 PMID： 25525870 DOI： 10.1016/j.cell.2014.12.009
Source DB: PubMed Journal: Cell ISSN： 0092-8674 Impact factor: 41.582