Literature DB >> 25524483

Vestibular schwannoma between 1 and 3 cm: importance of the tumor size in surgical and functional outcome.

Abolghasem Sepehrnia1, Hamid Borghei-Razavi2.   

Abstract

OBJECTIVE: The aim of the study was to compare the surgical and functional outcomes of the microsurgical osteoplastic retro-sigmoid approach in a semi-sitting position in two groups of patients with vestibular schwannomas (VSs) ranging from 1 to 3 cm in size.
METHOD: A 5-year retrospective evaluation was made of these two groups of patients with VS: Patients with VS sizes 1-<2 cm in maximal intra/extrameatal diameter (n=292) were assigned to group "A" and a matched group of patients with VS between 2 and 3 cm in size (n=154) were assigned to group "B".
RESULTS: Significant differences in postoperative outcomes (p<0.05) were found for facial nerve function of House-Brackmann grade I (94% group A vs. 78% group B) and preservation of preoperative hearing (51% group B vs. 34% group A). Patients with tumors sizes ranging between 1 and <2 cm exhibited total tumor removal with significantly higher facial nerve preservation and hearing function preservation rates compared with patients with tumors 2-3 cm in size.
CONCLUSION: Even a small increase in tumor size correlated with a significant reduction in good hearing and facial preservation postoperatively, which implies that tumor removal should be performed at the earliest stage possible. Furthermore, these results contradict recommending the wait-and-see approach for intra/extrameatal tumors.
Copyright © 2014 Elsevier B.V. All rights reserved.

Entities:  

Keywords:  Facial nerve functional preservation; Hearing preservation; Retrosigmoid approach; Semi-sitting position; Vestibular schwannoma

Mesh:

Year:  2014        PMID: 25524483     DOI: 10.1016/j.clineuro.2014.11.020

Source DB:  PubMed          Journal:  Clin Neurol Neurosurg        ISSN: 0303-8467            Impact factor:   1.876


  6 in total

1.  Surgical treatment of large vestibular schwannomas in patients with neurofibromatosis type 2: outcomes on facial nerve function and hearing preservation.

Authors:  Fu Zhao; Bo Wang; Zhijun Yang; Qiangyi Zhou; Peng Li; Xingchao Wang; Jing Zhang; Junting Zhang; Pinan Liu
Journal:  J Neurooncol       Date:  2018-02-28       Impact factor: 4.130

2.  Can an Imaging Marker of Consistency Predict Intraoperative Experience and Clinical Outcomes for Vestibular Schwannomas? A Retrospective Review.

Authors:  Robert J Macielak; Michael S Harris; Jameson K Mattingly; Varun S Shah; Luciano M Prevedello; Oliver F Adunka
Journal:  J Neurol Surg B Skull Base       Date:  2019-09-24

3.  Establishment of nomograms for the prediction of useful hearing loss in patients with neurofibromatosis type 2.

Authors:  Shi-Wei Li; Jing Zhang; Han-Lu Tang; Peng Li; Bo Wang; Fu Zhao; Pi-Nan Liu
Journal:  J Neurooncol       Date:  2021-11-09       Impact factor: 4.130

Review 4.  Audiovestibular symptoms and facial nerve function comparing microsurgery versus SRS for vestibular schwannomas: a systematic review and meta-analysis.

Authors:  Vinod Kumar Yakkala; Marco Mammi; Nayan Lamba; Renuka Kandikatla; Bhaskar Paliwal; Hoda Elshibiny; C Eduardo Corrales; Timothy R Smith; Rania A Mekary
Journal:  Acta Neurochir (Wien)       Date:  2022-08-13       Impact factor: 2.816

5.  The effects of different surgical positions (semi-sitting and lateral position) on the surgical outcomes of large vestibular schwannoma: study protocol for a randomized controlled trial.

Authors:  Xiaolong Wu; Xu Wang; Gang Song; Mingchu Li; Chengbei Hou; Ge Chen; Hongchuan Guo; Xinru Xiao; Jie Tang; Qingtang Lin; Yuhai Bao; Jiantao Liang
Journal:  Trials       Date:  2022-06-14       Impact factor: 2.728

6.  The association of age, body mass index, and frailty with vestibular schwannoma surgical morbidity.

Authors:  Khodayar Goshtasbi; Mehdi Abouzari; Sina Soltanzadeh-Zarandi; Brooke Sarna; Ariel Lee; Frank P K Hsu; Hamid R Djalilian
Journal:  Clin Neurol Neurosurg       Date:  2020-08-28       Impact factor: 1.876

  6 in total

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