Literature DB >> 25523560

Conventional drug therapy for inflammatory bowel disease.

Robert V Bryant1, Oliver Brain, Simon P L Travis.   

Abstract

Most patients with inflammatory bowel diseases (IBD) are offered conventional medical therapy, because emerging therapies for IBD are regulated by health-care jurisdiction and often limited to academic centres. This review distils current evidence to provide a pragmatic approach to conventional IBD therapy, including aminosalicylates, corticosteroids, thiopurines, methotrexate, calcineurin inhibitors, infliximab and adalimumab. It addresses drug efficacy, safety and salient practice points for optimal and appropriate practice.

Entities:  

Keywords:  Crohn’s disease; inflammatory bowel disease; ulcerative colitis

Mesh:

Substances:

Year:  2015        PMID: 25523560     DOI: 10.3109/00365521.2014.968864

Source DB:  PubMed          Journal:  Scand J Gastroenterol        ISSN: 0036-5521            Impact factor:   2.423


  20 in total

1.  IRF5 guides monocytes toward an inflammatory CD11c+ macrophage phenotype and promotes intestinal inflammation.

Authors:  Alastair L Corbin; Maria Gomez-Vazquez; Dorothée L Berthold; Moustafa Attar; Isabelle C Arnold; Fiona M Powrie; Stephen N Sansom; Irina A Udalova
Journal:  Sci Immunol       Date:  2020-05-22

2.  Ameliorating Active Ulcerative Colitis via an Orally Available Toll-Like Receptor-9 Modifier: A Prospective Open-Label, Multicenter Phase II Trial.

Authors:  Iris Dotan; Etgar Levy-Nissenbaum; Yehuda Chowers; Alexander Fich; Eran Israeli; Tomer Adar; Shimon Shteingart; Hermona Soreq; Eran Goldin
Journal:  Dig Dis Sci       Date:  2016-08-29       Impact factor: 3.199

Review 3.  Pharmacologic therapy for inflammatory bowel disease refractory to steroids.

Authors:  M P Martínez-Montiel; B Casis-Herce; G J Gómez-Gómez; A Masedo-González; C Yela-San Bernardino; C Piedracoba; G Castellano-Tortajada
Journal:  Clin Exp Gastroenterol       Date:  2015-08-17

Review 4.  Effects of Non-Starch Polysaccharides on Inflammatory Bowel Disease.

Authors:  Ying Nie; Qinlu Lin; Feijun Luo
Journal:  Int J Mol Sci       Date:  2017-06-27       Impact factor: 5.923

Review 5.  A Review of the Clinical Pharmacokinetics, Pharmacodynamics, and Immunogenicity of Vedolizumab.

Authors:  Maria Rosario; Nathanael L Dirks; Catherine Milch; Asit Parikh; Michael Bargfrede; Tim Wyant; Eric Fedyk; Irving Fox
Journal:  Clin Pharmacokinet       Date:  2017-11       Impact factor: 6.447

6.  Expression of decorin in intestinal tissues of mice with inflammatory bowel disease and its correlation with autophagy.

Authors:  Huazhou Zhao; Hongqing Xi; Bo Wei; Aizhen Cai; Ting Wang; Yi Wang; Xudong Zhao; Yanjing Song; Lin Chen
Journal:  Exp Ther Med       Date:  2016-11-15       Impact factor: 2.447

7.  Calcineurin B in CD4+ T Cells Prevents Autoimmune Colitis by Negatively Regulating the JAK/STAT Pathway.

Authors:  Andrea Mencarelli; Maurizio Vacca; Hanif Javanmard Khameneh; Enzo Acerbi; Alicia Tay; Francesca Zolezzi; Michael Poidinger; Alessandra Mortellaro
Journal:  Front Immunol       Date:  2018-02-19       Impact factor: 7.561

Review 8.  Dietary Strategies for Maintenance of Clinical Remission in Inflammatory Bowel Diseases: Are We There Yet?

Authors:  Konstantinos Gkikas; Konstantinos Gerasimidis; Simon Milling; Umer Z Ijaz; Richard Hansen; Richard K Russell
Journal:  Nutrients       Date:  2020-07-07       Impact factor: 5.717

9.  Calcineurin-mediated IL-2 production by CD11chighMHCII+ myeloid cells is crucial for intestinal immune homeostasis.

Authors:  Andrea Mencarelli; Hanif Javanmard Khameneh; Jan Fric; Maurizio Vacca; Sary El Daker; Baptiste Janela; Jing Ping Tang; Sabrina Nabti; Akhila Balachander; Tong Seng Lim; Florent Ginhoux; Paola Ricciardi-Castagnoli; Alessandra Mortellaro
Journal:  Nat Commun       Date:  2018-03-16       Impact factor: 14.919

10.  Polyphenolic Maqui Extract as a Potential Nutraceutical to Treat TNBS-Induced Crohn's Disease by the Regulation of Antioxidant and Anti-Inflammatory Pathways.

Authors:  Tamara Ortiz; Federico Argüelles-Arias; Matilde Illanes; Josefa-María García-Montes; Elena Talero; Laura Macías-García; Ana Alcudia; Victoria Vázquez-Román; Virginia Motilva; Manuel De-Miguel
Journal:  Nutrients       Date:  2020-06-11       Impact factor: 5.717

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