Literature DB >> 25523188

How many times should we screen a chemical library to discover an anticancer drug?

Miguel López-Lázaro1.   

Abstract

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Year:  2014        PMID： 25523188     DOI： 10.1016/j.drudis.2014.12.006

Source DB:  PubMed          Journal:  Drug Discov Today        ISSN： 1359-6446            Impact factor:   7.851


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  7 in total

1.  Fluorinated Analogues of Lepidilines A and C: Synthesis and Screening of Their Anticancer and Antiviral Activity.

Authors:  Grzegorz Mlostoń; Mateusz Kowalczyk; Małgorzata Celeda; Marcin Jasiński; Marta Denel-Bobrowska; Agnieszka B Olejniczak
Journal:  Molecules       Date:  2022-05-30       Impact factor: 4.927

2.  Two preclinical tests to evaluate anticancer activity and to help validate drug candidates for clinical trials.

Authors:  Miguel López-Lázaro
Journal:  Oncoscience       Date:  2015-02-20

3.  The migration ability of stem cells can explain the existence of cancer of unknown primary site. Rethinking metastasis.

Authors:  Miguel López-Lázaro
Journal:  Oncoscience       Date:  2015-05-01

4.  Selective amino acid restriction therapy (SAART): a non-pharmacological strategy against all types of cancer cells.

Authors:  Miguel López-Lázaro
Journal:  Oncoscience       Date:  2015-11-10

5.  Cytotoxic effects of Pseudocerastes persicus venom and its HPLC fractions on lung cancer cells.

Authors:  Benyamin Shahbazi; Zahra Salehi Najafabadi; Hamidreza Goudarzi; Mahnaz Sajadi; Fatemeh Tahoori; Masoumeh Bagheri
Journal:  J Venom Anim Toxins Incl Trop Dis       Date:  2019-09-16

6.  Ruthenium (II) complex cis-[RuII(ŋ2-O2CC7H7O2)(dppm)2]PF6-hmxbato induces ROS-mediated apoptosis in lung tumor cells producing selective cytotoxicity.

Authors:  Mônica Soares Costa; Yasmim Garcia Gonçalves; Bruna Cristina Borges; Marcelo José Barbosa Silva; Martin Krähenbühl Amstalden; Tássia Rafaella Costa; Lusânia Maria Greggi Antunes; Renata Santos Rodrigues; Veridiana de Melo Rodrigues; Eduardo de Faria Franca; Mariana Alves Pereira Zoia; Thaise Gonçalves de Araújo; Luiz Ricardo Goulart; Gustavo Von Poelhsitz; Kelly Aparecida Geraldo Yoneyama
Journal:  Sci Rep       Date:  2020-09-21       Impact factor: 4.379

7.  In Vitro Anticancer and Cancer-Preventive Activity of New Triterpene Glycosides from the Far Eastern Starfish Solaster pacificus.

Authors:  Timofey V Malyarenko; Olesya S Malyarenko; Alla A Kicha; Anatoly I Kalinovsky; Pavel S Dmitrenok; Natalia V Ivanchina
Journal:  Mar Drugs       Date:  2022-03-20       Impact factor: 5.118
  7 in total

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