Literature DB >> 25522848

Relationship of prenatal depression and comorbidities to infant outcomes.

Heather A Flynn1, Nicole McBride2, Aura Cely2, Yuxia Wang1, Julie DeCesare3.   

Abstract

OBJECTIVE: The purpose of this study was to provide information on the effect of prenatal depression and anxiety as assessed in the context of obstetrical care on key infant outcomes (gestational age at birth, birth weight, and APGAR scores), while simultaneously considering interactions with maternal medical conditions among primarily Medicaid enrollees.
METHODS: Obstetrical medical records of 419 women presenting consecutively for prenatal care at a health system serving primarily Medicaid patients were examined. Information on maternal characteristics (age, race, education) and maternal medical health (BMI, high blood pressure, diabetes, and kidney problems), as well as mental health information, was extracted. Depression was assessed as part of routine care using the Patient Health Questionnaire-9 (PHQ-9), and any documentation of depression or anxiety by the obstetrics clinician was also used in the analyses.
RESULTS: Approximately one-third of the sample showed some evidence of prenatal depression, either based on PHQ-9 score (≥10) or clinician documentation of depression, and close to 10% showed evidence of anxiety. Multivariate analyses showed significant interactions between depression and anxiety on gestational age and birth weight, between depression and high blood pressure on gestational age, and also between anxiety and kidney problems on gestational age.
CONCLUSION: Among this sample, the effect of maternal depression and anxiety on birth outcomes was more evident when considered along with maternal chronic medical conditions. This information may be used to assist prenatal care clinicians to develop risk assessment based on knowledge of multiple risk factors that may exert and additive influence on poor birth outcomes.

Entities:  

Keywords:  prenatal depression

Mesh:

Year:  2014        PMID: 25522848     DOI: 10.1017/S1092852914000716

Source DB:  PubMed          Journal:  CNS Spectr        ISSN: 1092-8529            Impact factor:   3.790


  4 in total

1.  Perinatal Anxiety and Depression in Minority Women.

Authors:  Susan Gennaro; Caitlin OʼConnor; Elizabeth Anne McKay; Anne Gibeau; Melanie Aviles; Jacqueline Hoying; Bernadette Mazurek Melnyk
Journal:  MCN Am J Matern Child Nurs       Date:  2020 May/Jun       Impact factor: 1.412

2.  Adherence to and Persistence with Antidepressant Medication during Pregnancy: Does It Differ by the Class of Antidepressant Medication Prescribed?

Authors:  Kamala Adhikari; Scott B Patten; Sangmin Lee; Amy Metcalfe
Journal:  Can J Psychiatry       Date:  2018-09-25       Impact factor: 4.356

3.  Mood instability, depression, and anxiety in pregnancy and adverse neonatal outcomes.

Authors:  Hua Li; Angela Bowen; Rudy Bowen; Nazeem Muhajarine; Lloyd Balbuena
Journal:  BMC Pregnancy Childbirth       Date:  2021-08-25       Impact factor: 3.007

4.  Neighbourhood socioeconomic status modifies the association between anxiety and depression during pregnancy and preterm birth: a Community-based Canadian cohort study.

Authors:  Kamala Adhikari; Scott B Patten; Tyler Williamson; Alka B Patel; Shahirose Premji; Suzanne Tough; Nicole Letourneau; Gerald Giesbrecht; Amy Metcalfe
Journal:  BMJ Open       Date:  2020-02-10       Impact factor: 2.692

  4 in total

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