Literature DB >> 25522821

Antitumor effect of boron nitride nanotubes in combination with thermal neutron irradiation on BNCT.

Hiroyuki Nakamura1, Hayato Koganei2, Tatsuro Miyoshi2, Yoshinori Sakurai3, Koji Ono3, Minoru Suzuki3.   

Abstract

The first BNCT antitumor effects of BNNTs toward B16 melanoma cells were demonstrated. The use of DSPE-PEG2000 was effective for preparation of the BNNT-suspended aqueous solution. BNNT-DSPE-PEG2000 accumulated in B16 melanoma cells approximately three times higher than BSH and the higher BNCT antitumor effect was observed in the cells treated with BNNT-DSPE-PEG2000 compared to those treated with BSH, indicating that BNNT-DSPE-PEG2000 would be a possible candidate as a boron delivery vehicle for BNCT.
Copyright © 2014 Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  Antitumor effect; B16 melanoma cells; Boron neutron capture therapy (BNCT); Boron nitride nanotubes (BNNTs); Colony-forming assay

Mesh：

Substances：

Year:  2014        PMID： 25522821     DOI： 10.1016/j.bmcl.2014.12.005

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN： 0960-894X            Impact factor:   2.823


  6 in total

Review 1.  In Vitro and In Vivo Cytotoxicity of Boron Nitride Nanotubes: A Systematic Review.

Authors:  Akesh Babu Kakarla; Ing Kong
Journal:  Nanomaterials (Basel)       Date:  2022-06-15       Impact factor: 5.719

2.  An Assessment of the Potential Use of BNNTs for Boron Neutron Capture Therapy.

Authors:  Tiago H Ferreira; Marcelo C Miranda; Zildete Rocha; Alexandre S Leal; Dawidson A Gomes; Edesia M B Sousa
Journal:  Nanomaterials (Basel)       Date:  2017-04-12       Impact factor: 5.076

3.  Opportunistic dose amplification for proton and carbon ion therapy via capture of internally generated thermal neutrons.

Authors:  Mitra Safavi-Naeini; Andrew Chacon; Susanna Guatelli; Daniel R Franklin; Keith Bambery; Marie-Claude Gregoire; Anatoly Rosenfeld
Journal:  Sci Rep       Date:  2018-11-02       Impact factor: 4.379

4.  Cancer Cell-Membrane Biomimetic Boron Nitride Nanospheres for Targeted Cancer Therapy.

Authors:  Shini Feng; Yajing Ren; Hui Li; Yunfei Tang; Jinyu Yan; Zeyuan Shen; Huijie Zhang; Fuxue Chen
Journal:  Int J Nanomedicine       Date:  2021-03-11

5.  Targeting glioma stem cells enhances anti-tumor effect of boron neutron capture therapy.

Authors:  Ting Sun; Yanyan Li; Yulun Huang; Zizhu Zhang; Weilian Yang; Ziwei Du; Youxin Zhou
Journal:  Oncotarget       Date:  2016-07-12

6.  pH-responsive charge-reversal polymer-functionalized boron nitride nanospheres for intracellular doxorubicin delivery.

Authors:  Shini Feng; Huijie Zhang; Chunyi Zhi; Xiao-Dong Gao; Hideki Nakanishi
Journal:  Int J Nanomedicine       Date:  2018-01-31
  6 in total

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