Literature DB >> 25521972

A new ethical landscape of prenatal testing: individualizing choice to serve autonomy and promote public health: a radical proposal.

Christian Munthe.   

Abstract

A new landscape of prenatal testing (PNT) is presently developing, including new techniques for risk-reducing, non-invasive sampling of foetal DNA and drastically enhanced possibilities of what may be rapidly and precisely analysed, surrounded by a growing commercial genetic testing industry and a general trend of individualization in healthcare policies. This article applies a set of established ethical notions from past debates on PNT for analysing PNT screening-programmes in this new situation. While some basic challenges of PNT stay untouched, the new development supports a radical individualization of how PNT screening is organized. This reformation is, at the same time, difficult to reconcile with responsible spending of resources in a publicly funded healthcare context. Thus, while the ethical imperative of individualization holds and applies to PNT, the new landscape of PNT provides reasons to start rolling back the type of mass-screening programmes currently established in many countries. Instead, more limited offers are suggested, based on considerations of severity of conditions and optimized to simultaneously serve reproductive autonomy and public health within an acceptable frame of priorities. The new landscape of PNT furthermore underscores the ethical importance of supporting and including people with disabilities. For the very same reason, no ban on what may be analysed using PNT in the new landscape should be applied, although private offers must, of course, conform to strict requirements of respecting reproductive autonomy and what that means in terms of counselling.
© 2014 John Wiley & Sons Ltd.

Entities:  

Keywords:  NIPT; WGS; arrayCGH; disability; prenatal diagnosis; prenatal screening; reproductive ethics

Mesh:

Year:  2015        PMID: 25521972     DOI: 10.1111/bioe.12126

Source DB:  PubMed          Journal:  Bioethics        ISSN: 0269-9702            Impact factor:   1.898


  11 in total

1.  Structurating Expanded Genetic Carrier Screening: A Longitudinal Analysis of Online News Coverage.

Authors:  Heather E Canary; Yvonne K Clark; Avery Holton
Journal:  J Health Commun       Date:  2018-05-25

Review 2.  Prenatal and pre-implantation genetic diagnosis.

Authors:  Joris Robert Vermeesch; Thierry Voet; Koenraad Devriendt
Journal:  Nat Rev Genet       Date:  2016-09-15       Impact factor: 53.242

3.  Prenatal genetic testing for cystic fibrosis: a systematic review of clinical effectiveness and an ethics review.

Authors:  Sharon J M Kessels; Drew Carter; Benjamin Ellery; Skye Newton; Tracy L Merlin
Journal:  Genet Med       Date:  2019-08-30       Impact factor: 8.822

4.  Non-invasive prenatal testing for aneuploidy and beyond: challenges of responsible innovation in prenatal screening.

Authors:  Wybo Dondorp; Guido de Wert; Yvonne Bombard; Diana W Bianchi; Carsten Bergmann; Pascal Borry; Lyn S Chitty; Florence Fellmann; Francesca Forzano; Alison Hall; Lidewij Henneman; Heidi C Howard; Anneke Lucassen; Kelly Ormond; Borut Peterlin; Dragica Radojkovic; Wolf Rogowski; Maria Soller; Aad Tibben; Lisbeth Tranebjærg; Carla G van El; Martina C Cornel
Journal:  Eur J Hum Genet       Date:  2015-03-18       Impact factor: 4.246

Review 5.  Non-invasive prenatal testing for fetal chromosome abnormalities: review of clinical and ethical issues.

Authors:  Jean Gekas; Sylvie Langlois; Vardit Ravitsky; François Audibert; David Gradus van den Berg; Hazar Haidar; François Rousseau
Journal:  Appl Clin Genet       Date:  2016-02-04

6.  Role of Psychosocial Factors and Health Literacy in Pregnant Women's Intention to Use a Decision Aid for Down Syndrome Screening: A Theory-Based Web Survey.

Authors:  Agathe Delanoë; Johanie Lépine; Stéphane Turcotte; Maria Esther Leiva Portocarrero; Hubert Robitaille; Anik Mc Giguère; Brenda J Wilson; Holly O Witteman; Isabelle Lévesque; Laurence Guillaumie; France Légaré
Journal:  J Med Internet Res       Date:  2016-10-28       Impact factor: 5.428

7.  Qualifying choice: ethical reflection on the scope of prenatal screening.

Authors:  Greg Stapleton
Journal:  Med Health Care Philos       Date:  2017-06

8.  Just choice: a Danielsian analysis of the aims and scope of prenatal screening for fetal abnormalities.

Authors:  Greg Stapleton; Wybo Dondorp; Peter Schröder-Bäck; Guido de Wert
Journal:  Med Health Care Philos       Date:  2019-12

9.  Ethical issues in preconception genetic carrier screening.

Authors:  Ulrik Kihlbom
Journal:  Ups J Med Sci       Date:  2016-07-08       Impact factor: 2.384

10.  Should pregnant women be charged for non-invasive prenatal screening? Implications for reproductive autonomy and equal access.

Authors:  Robert-Jan H Galjaard; Inez D de Beaufort; Eline M Bunnik; Adriana Kater-Kuipers
Journal:  J Med Ethics       Date:  2019-09-16       Impact factor: 2.903

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.