Literature DB >> 25521079

Treatment costs for advanced prostate cancer using luteinizing hormone-releasing hormone agonists: a solid biodegradable leuprorelin implant versus other formulations.

Axel S Merseburger1, Thomas Björk2, James Whitehouse3, Davide Meani4.   

Abstract

AIM: To compare treatment costs with alternative luteinizing hormone-releasing hormone (LHRH) agonist preparations and determine whether a leuprorelin solid implant is associated with potential cost savings. PATIENTS &
METHODS: A hypothetical population of 1000 prostate cancer patients was apportioned between the three most commonly-prescribed LHRH agonist preparations. Differentiated annual costs for 1- and 3-monthly formulations were calculated for France, Germany, Italy, Spain, the UK (EU5) and Sweden, and compared with the leuprorelin solid implant.
RESULTS: Compared with alternative formulations, leuprorelin solid implants had potential annual cost savings/1000 patients of €353,000 (EU5) and €699,000 (Sweden; 1-month formulations), and €259,000 (EU5) and €300,000 (Sweden; 3-month formulations).
CONCLUSION: The leuprorelin solid implant was associated with potential cost savings compared with the most commonly used LHRH agonist preparations.

Entities:  

Keywords:  costs; economics; leuprorelin; luteinizing hormone-releasing hormone agonists; prostate cancer

Mesh:

Substances:

Year:  2014        PMID: 25521079     DOI: 10.2217/cer.14.82

Source DB:  PubMed          Journal:  J Comp Eff Res        ISSN: 2042-6305            Impact factor:   1.744


  7 in total

1.  Testosterone suppression with a unique form of leuprorelin acetate as a solid biodegradable implant in patients with advanced prostate cancer: results from four trials and comparison with the traditional leuprorelin acetate microspheres formulation.

Authors:  Mladen Solarić; Anders Bjartell; Ursula Thyroff-Friesinger; Davide Meani
Journal:  Ther Adv Urol       Date:  2017-04-18

Review 2.  Practical differences between luteinizing hormone-releasing hormone agonists in prostate cancer: perspectives across the spectrum of care.

Authors:  Davide Meani; Mladen Solarić; Harri Visapää; Rose-Marie Rosén; Robert Janknegt; Majana Soče
Journal:  Ther Adv Urol       Date:  2017-11-23

3.  Switching from an LHRH Antagonist to an LHRH Agonist: A Case Report of 10 Finnish Patients with Advanced Prostate Cancer.

Authors:  Harri Visapää
Journal:  Oncol Ther       Date:  2017-02-09

4.  Abiraterone acetate plus LHRH therapy versus abiraterone acetate while sparing LHRH therapy in patients with progressive, metastatic and chemotherapy-naïve, castration-resistant prostate cancer (SPARE): study protocol for a randomized controlled trial.

Authors:  Carsten-Henning Ohlmann; Michelle Jäschke; Peter Jaehnig; Susane Krege; Jürgen Gschwend; Heidrun Rexer; Michael Stöckle
Journal:  Trials       Date:  2017-10-04       Impact factor: 2.279

5.  The current status of hormone treatment for prostate cancer patients in Korean real-world practice: a multi-institutional observational study.

Authors:  Jung Kwon Kim; Jung Jun Kim; Taek Won Gang; Tae Kyun Kwon; Hong Sup Kim; Seung Chul Park; Jae-Shin Park; Jong-Yeon Park; Seok Joong Yoon; Youn-Soo Jeon; Jin Seon Cho; Kwan Joong Joo; Sung-Hoo Hong; Seok-Soo Byun
Journal:  Asian J Androl       Date:  2019 Mar-Apr       Impact factor: 3.285

6.  Enzalutamide in chemotherapy-naive patients with metastatic castration-resistant prostate cancer: A retrospective Korean multicenter study in a real-world setting.

Authors:  Seung Il Jung; Myung Soo Kim; Chang Wook Jeong; Cheol Kwak; Sung Kyu Hong; Seok Ho Kang; Jae Young Joung; Seung Hwan Lee; Seok Joong Yun; Tae-Hwan Kim; Sung Woo Park; Seong Soo Jeon; Minyong Kang; Ji Youl Lee; Byung Ha Chung; Jun Hyuk Hong; Hanjong Ahn; Choung-Soo Kim; Dong Deuk Kwon
Journal:  Investig Clin Urol       Date:  2019-12-10

7.  Redox-Sensitive Nanocomplex for Targeted Delivery of Melittin.

Authors:  Bei Cheng; Peisheng Xu
Journal:  Toxins (Basel)       Date:  2020-09-10       Impact factor: 4.546

  7 in total

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