Khalid F AlHabib1, Tarek Kashour2, Abdelfatah A Elasfar3, Hussam Alfaleh2, Ahmad Hersi2, Mostafa Alshamiri2, Fayez Alshaer2, Layth Mimish4, Ali Almasood5, Waleed AlHabeeb6, Saleh AlGhamdi7, Abdullah Ghabashi8, KaziNur Asfina2, Hani Altaradi2, Omar Alnobani2, Nour Alkamel2, Lukman Thalib9. 1. Department of Cardiac Sciences, King Fahad Cardiac Center, College of Medicine, King Saud University, Riyadh, Saudi Arabia khalidalhabib13@hotmail.com. 2. Department of Cardiac Sciences, King Fahad Cardiac Center, College of Medicine, King Saud University, Riyadh, Saudi Arabia. 3. Prince Salman Heart Center, King Fahd Medical City, Riyadh, Saudi Arabia Cardiology Department, Tanta University, Tanta, Egypt. 4. King Abdulaziz University Hospital, Jeddah, Saudi Arabia. 5. Prince Sultan Cardiac Center, Riyadh, Saudi Arabia. 6. Department of Cardiac Sciences, King Fahad Cardiac Center, College of Medicine, King Saud University, Riyadh, Saudi Arabia King Faisal Cardiac Center, King Faisal Specialist Hospital, Riyadh, Saudi Arabia. 7. Madina Cardiac Center, Al Madina Al Monaoarah, Saudi Arabia. 8. Prince Sultan Cardiac Center, Hafouf, Saudi Arabia. 9. Faculty of Medicine, Health Sciences Centre, Kuwait University, Kuwait city, Kuwait.
Abstract
AIM: The heart function assessment registry trial in Saudi Arabia (HEARTS) is a national multicenter project that compared de novo versus acute-on-chronic heart failure (ACHF). METHODS AND RESULTS: This is a prospective registry in 18 hospitals in Saudi Arabia between October 2009 and December 2010. The study enrolled 2610 patients: 940 (36%) de novo and 1670 (64%) ACHF. Patients with ACHF were significantly older (62.2 vs 60 years), less likely to be males (64% vs 69%) or smokers (31.6% vs 36.7%), and more likely to have history of diabetes mellitus (65.7% vs 61.3%), hypertension (74% vs 65%), and severe left ventricular dysfunction (52% vs 40%). The ACHF group had a higher adjusted 3-year mortality rate (hazard ratio, 1.6; 95% confidence interval [CI] 1.3-2.0; P < .001). CONCLUSION: Patients with ACHF had significantly higher long-term mortality rates than those with de novo acute heart failure (HF). Multidisciplinary HF disease management programs are highly needed for such high-risk populations.
AIM: The heart function assessment registry trial in Saudi Arabia (HEARTS) is a national multicenter project that compared de novo versus acute-on-chronic heart failure (ACHF). METHODS AND RESULTS: This is a prospective registry in 18 hospitals in Saudi Arabia between October 2009 and December 2010. The study enrolled 2610 patients: 940 (36%) de novo and 1670 (64%) ACHF. Patients with ACHF were significantly older (62.2 vs 60 years), less likely to be males (64% vs 69%) or smokers (31.6% vs 36.7%), and more likely to have history of diabetes mellitus (65.7% vs 61.3%), hypertension (74% vs 65%), and severe left ventricular dysfunction (52% vs 40%). The ACHF group had a higher adjusted 3-year mortality rate (hazard ratio, 1.6; 95% confidence interval [CI] 1.3-2.0; P < .001). CONCLUSION:Patients with ACHF had significantly higher long-term mortality rates than those with de novo acute heart failure (HF). Multidisciplinary HF disease management programs are highly needed for such high-risk populations.
Authors: Hussam AlFaleh; Abdelfatah A Elasfar; Anhar Ullah; Khalid F AlHabib; Ahmad Hersi; Layth Mimish; Ali Almasood; Saleh Al Ghamdi; Abdullah Ghabashi; Asif Malik; Gamal A Hussein; Mushabab Al-Murayeh; Ahmed Abuosa; Waleed Al Habeeb; Tarek S Kashour Journal: BMC Cardiovasc Disord Date: 2016-05-20 Impact factor: 2.298