Literature DB >> 25520184

Neurological and functional recovery after thoracic spinal cord injury.

Brian A Lee, Benjamin E Leiby, Ralph J Marino.   

Abstract

OBJECTIVE: To describe neurological and functional outcomes after traumatic paraplegia.
DESIGN: Retrospective analysis of longitudinal database.
SETTING: Spinal Cord Injury Model Systems. PARTICIPANTS: Six hundred sixty-one subjects enrolled in the Spinal Cord Injury Model Systems database, injured between 2000 and 2011, with initial neurological level of injury from T2-12. Two hundred sixty-five subjects had second neurological exams and 400 subjects had Functional Independence Measure (FIM) scores ≥6 months after injury. OUTCOME MEASURES: American Spinal Injury Association Impairment Scale (AIS) grade, sensory level (SL), lower extremity motor scores (LEMS), and FIM.
RESULTS: At baseline, 73% of subjects were AIS A, and among them, 15.5% converted to motor incomplete. The mean SL increase for subjects with an AIS A grade was 0.33 ± 0.21; 86% remained within two levels of baseline. Subjects with low thoracic paraplegia (T10-12) demonstrated greater LEMS gain than high paraplegia (T2-9), and also had higher 1-year FIM scores, which had not been noted in earlier reports. Better FIM scores were also correlated with better AIS grades, younger age and increase in AIS grade. Ability to walk at 1 year was associated with low thoracic injury, higher initial LEMS, incomplete injury and increase in AIS grade.
CONCLUSION: Little neurological recovery is seen in persons with complete thoracic SCI, especially with levels above T10. Persons who are older at the time of injury have poorer functional recovery than younger persons. Conversion to a better AIS grade is associated with improvement in self-care and mobility at 1 year.

Entities:  

Keywords:  Outcomes; Paraplegia; Recovery; Rehabilitation; Spinal cord injuries

Mesh:

Year:  2014        PMID: 25520184      PMCID: PMC4725794          DOI: 10.1179/2045772314Y.0000000280

Source DB:  PubMed          Journal:  J Spinal Cord Med        ISSN: 1079-0268            Impact factor:   1.985


  23 in total

1.  Proposal and validation of a clinical trunk control test in individuals with spinal cord injury.

Authors:  J Quinzaños; A R Villa; A A Flores; R Pérez
Journal:  Spinal Cord       Date:  2014-04-08       Impact factor: 2.772

2.  Upper- and lower-extremity motor recovery after traumatic cervical spinal cord injury: an update from the national spinal cord injury database.

Authors:  Ralph J Marino; Stephen Burns; Daniel E Graves; Benjamin E Leiby; Steven Kirshblum; Daniel P Lammertse
Journal:  Arch Phys Med Rehabil       Date:  2011-03       Impact factor: 3.966

3.  The impact of sacral sensory sparing in motor complete spinal cord injury.

Authors:  Steven Kirshblum; Amanda Botticello; Daniel P Lammertse; Ralph J Marino; Anthony E Chiodo; Amitabh Jha
Journal:  Arch Phys Med Rehabil       Date:  2011-03       Impact factor: 3.966

4.  Neurologic recovery after traumatic spinal cord injury: data from the Model Spinal Cord Injury Systems.

Authors:  R J Marino; J F Ditunno; W H Donovan; F Maynard
Journal:  Arch Phys Med Rehabil       Date:  1999-11       Impact factor: 3.966

5.  Characteristics of the Functional Independence Measure in traumatic spinal cord injury.

Authors:  K M Hall; M E Cohen; J Wright; M Call; P Werner
Journal:  Arch Phys Med Rehabil       Date:  1999-11       Impact factor: 3.966

6.  Characterization of neurological recovery following traumatic sensorimotor complete thoracic spinal cord injury.

Authors:  J Zariffa; J L K Kramer; J W Fawcett; D P Lammertse; A R Blight; J Guest; L Jones; S Burns; M Schubert; M Bolliger; A Curt; J D Steeves
Journal:  Spinal Cord       Date:  2010-10-12       Impact factor: 2.772

7.  Seated reach distance and trunk excursion accurately reflect dynamic postural control in individuals with motor-incomplete spinal cord injury.

Authors:  E C Field-Fote; S S Ray
Journal:  Spinal Cord       Date:  2010-02-16       Impact factor: 2.772

8.  Traumatic thoracic ASIA A examinations and potential for clinical trials.

Authors:  James S Harrop; Mitchell Gil Maltenfort; Fred H Geisler; William Coleman; Linda A T Jones; Edward Wirth; Alexander Vaccaro
Journal:  Spine (Phila Pa 1976)       Date:  2009-11-01       Impact factor: 3.468

9.  ASIA impairment scale conversion in traumatic SCI: is it related with the ability to walk? A descriptive comparison with functional ambulation outcome measures in 273 patients.

Authors:  J J van Middendorp; A J F Hosman; M H Pouw; H Van de Meent
Journal:  Spinal Cord       Date:  2008-12-23       Impact factor: 2.772

Review 10.  Providing the clinical basis for new interventional therapies: refined diagnosis and assessment of recovery after spinal cord injury.

Authors:  A Curt; M E Schwab; V Dietz
Journal:  Spinal Cord       Date:  2004-01       Impact factor: 2.772

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Authors:  Pamela A Kisala; Aaron J Boulton; Mary D Slavin; Matthew L Cohen; Tamra Keeney; Pengsheng Ni; Denise Tate; Allen W Heinemann; Susan Charlifue; Denise C Fyffe; Elizabeth R Felix; Alan M Jette; David S Tulsky
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3.  International surveillance study in acute spinal cord injury confirms viability of multinational clinical trials.

Authors:  Armin Curt; Catherine R Jutzeler; Lucie Bourguignon; Bobo Tong; Fred Geisler; Martin Schubert; Frank Röhrich; Marion Saur; Norbert Weidner; Rüdiger Rupp; Yorck-Bernhard B Kalke; Rainer Abel; Doris Maier; Lukas Grassner; Harvinder S Chhabra; Thomas Liebscher; Jacquelyn J Cragg; John Kramer
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4.  Relationship of American Spinal Injury Association Impairment Scale Grade to Post-injury Hospitalization and Costs in Thoracic Spinal Cord Injury.

Authors:  Ellen M Dukes; Steven Kirshblum; Alex A Aimetti; Sarah S Qin; Rebecca K Bornheimer; Gerry Oster
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5.  Association Between SCIM III Total Scores and Individual Item Scores to Predict Independence With ADLs in Persons With Spinal Cord Injury.

Authors:  Kei Unai; Osamu Uemura; Ryo Takemura; Michiyuki Kawakami; Meigen Liu
Journal:  Arch Rehabil Res Clin Transl       Date:  2019-10-23

6.  Acute Implantation of a Bioresorbable Polymer Scaffold in Patients With Complete Thoracic Spinal Cord Injury: 24-Month Follow-up From the INSPIRE Study.

Authors:  Kee D Kim; K Stuart Lee; Domagoj Coric; James S Harrop; Nicholas Theodore; Richard M Toselli
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7.  Translation, Cross-cultural Adaptation, and Psychometric Properties of the Turkish Version of the Self-care Ability Scale for the Elderly.

Authors:  Mehmet Özkeskin; Fatih Özden; Sevnaz Şahin
Journal:  Ann Geriatr Med Res       Date:  2021-06-25

8.  Trends in Rates of ASIA Impairment Scale Conversion in Traumatic Complete Spinal Cord Injury.

Authors:  Ralph J Marino; Michael Leff; Diana D Cardenas; Jayne Donovan; David Chen; Steve Kirshblum; Benjamin E Leiby
Journal:  Neurotrauma Rep       Date:  2020-11-13

9.  Crossed Corticospinal Facilitation Between Arm and Trunk Muscles Correlates With Trunk Control After Spinal Cord Injury.

Authors:  Shin-Yi Chiou; Paul H Strutton
Journal:  Front Hum Neurosci       Date:  2020-10-23       Impact factor: 3.169

10.  NeuroRegen Scaffolds Combined with Autologous Bone Marrow Mononuclear Cells for the Repair of Acute Complete Spinal Cord Injury: A 3-Year Clinical Study.

Authors:  Wugui Chen; Ying Zhang; Sizhen Yang; Jing Sun; Hao Qiu; Xu Hu; Xiaojian Niu; Zhifeng Xiao; Yannan Zhao; Yue Zhou; Jianwu Dai; Tongwei Chu
Journal:  Cell Transplant       Date:  2020 Jan-Dec       Impact factor: 4.064

  10 in total

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