PURPOSE: Synthetic ovarian hormones contained in oral contraceptives (OC) may alter the aerobic capacity and lipid metabolism in oral contraceptive users (OC+) compared with non-users (OC-). The aim of this study was thus to investigate the differences between OC- and OC+ (1) in cardiorespiratory parameters at the anaerobic threshold (AT) and at the maximal aerobic capacity and (2) in the exercise intensity (Lipoxmax) at which lipid oxidation rate is maximal (MLOR). METHODS: Twenty-one healthy untrained women (22.0 ± 0.6 years old) who took OC (OC+; low-dose monophasic OC, n = 11) or not (OC-; n = 10) performed two experimental exercise sessions. In the first one, cardiorespiratory parameters at the AT and at the maximal aerobic capacity were assessed during a maximal incremental exercise session. In the second one, Lipoxmax and MLOR were measured during a submaximal incremental exercise session. RESULTS: No significant difference was observed in cardiorespiratory parameters at the AT and at the maximal aerobic capacity between OC+ and OC- women. OC+ women showed higher MLOR (7.6 ± 1.9 vs 4.6 ± 1.0 mg min(-1) kg FFM(-1); p < 0.01) that was elicited by higher Lipoxmax (45.2 ± 5.2 vs 36.2 ± 4.1 % of VO2max; p < 0.001) compared to OC- women. CONCLUSIONS: OC+ and OC- women did not differ in cardiorespiratory parameters at the AT and at the maximal aerobic capacity. However, OC+ women show higher MLOR and Lipoxmax compared with OC- women. The hormonal status appears to be an important MLOR and Lipoxmax determinant in untrained women.
PURPOSE: Synthetic ovarian hormones contained in oral contraceptives (OC) may alter the aerobic capacity and lipid metabolism in oral contraceptive users (OC+) compared with non-users (OC-). The aim of this study was thus to investigate the differences between OC- and OC+ (1) in cardiorespiratory parameters at the anaerobic threshold (AT) and at the maximal aerobic capacity and (2) in the exercise intensity (Lipoxmax) at which lipid oxidation rate is maximal (MLOR). METHODS: Twenty-one healthy untrained women (22.0 ± 0.6 years old) who took OC (OC+; low-dose monophasic OC, n = 11) or not (OC-; n = 10) performed two experimental exercise sessions. In the first one, cardiorespiratory parameters at the AT and at the maximal aerobic capacity were assessed during a maximal incremental exercise session. In the second one, Lipoxmax and MLOR were measured during a submaximal incremental exercise session. RESULTS: No significant difference was observed in cardiorespiratory parameters at the AT and at the maximal aerobic capacity between OC+ and OC- women. OC+ women showed higher MLOR (7.6 ± 1.9 vs 4.6 ± 1.0 mg min(-1) kg FFM(-1); p < 0.01) that was elicited by higher Lipoxmax (45.2 ± 5.2 vs 36.2 ± 4.1 % of VO2max; p < 0.001) compared to OC- women. CONCLUSIONS: OC+ and OC- women did not differ in cardiorespiratory parameters at the AT and at the maximal aerobic capacity. However, OC+ women show higher MLOR and Lipoxmax compared with OC- women. The hormonal status appears to be an important MLOR and Lipoxmax determinant in untrained women.
Authors: N R de Melo; J M Aldrighi; D Faggion; V R O Y Reyes; J B Souza; C E Fernandes; E Larson Journal: Contraception Date: 2004-07 Impact factor: 3.375
Authors: Gretchen A Casazza; Kevin A Jacobs; Sang-Hoon Suh; Benjamin F Miller; Michael A Horning; George A Brooks Journal: J Appl Physiol (1985) Date: 2004-02-27
Authors: Kirsty J Elliott-Sale; Kelly L McNulty; Paul Ansdell; Stuart Goodall; Kirsty M Hicks; Kevin Thomas; Paul A Swinton; Eimear Dolan Journal: Sports Med Date: 2020-10 Impact factor: 11.136