H Duan1, M Hoffmann. 1. Klinische Abteilung für Nuklearmedizin, Universitätsklinik für Radiologie und Nuklearmedizin, Medizinische Universität Wien, Wien, Österreich.
Abstract
METHODICAL INNOVATIONS: Selective internal radiotherapy (SIRT) is a safe and efficacious, minimally invasive procedure to treat primary and secondary unresectable liver tumors. For hepatocellular carcinoma (HCC), SIRT has proven to be a well-tolerated therapy option even in advanced stages of disease. STANDARD RADIOLOGICAL METHODS: In cases of portal vein thrombosis SIRT is the alternative to transarterial chemoembolization (TACE). PERFORMANCE: The role of SIRT regarding downstaging and bridging to transplantation is promising and SIRT has also been shown to be highly effective and well-tolerated in metastastic liver disease. ACHIEVEMENTS: The results of prospective randomized trials are awaited to prove the efficiency and safety of SIRT described in numerous retrospective and prospective non-randomized studies. PRACTICAL RECOMMENDATIONS: The indications are established within the framework of a tumor board.
METHODICAL INNOVATIONS: Selective internal radiotherapy (SIRT) is a safe and efficacious, minimally invasive procedure to treat primary and secondary unresectable liver tumors. For hepatocellular carcinoma (HCC), SIRT has proven to be a well-tolerated therapy option even in advanced stages of disease. STANDARD RADIOLOGICAL METHODS: In cases of portal vein thrombosis SIRT is the alternative to transarterial chemoembolization (TACE). PERFORMANCE: The role of SIRT regarding downstaging and bridging to transplantation is promising and SIRT has also been shown to be highly effective and well-tolerated in metastastic liver disease. ACHIEVEMENTS: The results of prospective randomized trials are awaited to prove the efficiency and safety of SIRT described in numerous retrospective and prospective non-randomized studies. PRACTICAL RECOMMENDATIONS: The indications are established within the framework of a tumor board.
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