Literature DB >> 25519865

Failure to identify or effectively manage prescription opioid dependence acted as a gateway to heroin use-buprenorphine/naloxone treatment and recovery in a surgical patient.

Stephen Conroy1, Duncan Hill2.   

Abstract

The prescribing of opioid pain medication has increased markedly in recent years, with strong opioid dispensing increasing 18-fold in Tayside, Scotland since 1995. Despite this, little data is available to quantify the problem of opioid pain medication dependence (OPD) and until recently there was little guidance on best-practice treatment. We report the case of a young mother prescribed dihydrocodeine for postoperative pain relief who became opioid dependent. When her prescription was stopped without support, she briefly used heroin to overcome her withdrawal. After re-exposure to dihydrocodeine following surgery 9 years later and treatment with methadone for dependency, she was transferred to buprenorphine/naloxone. In our clinical experience and in agreement with Department of Health and Royal College of General Practitioner guidance, buprenorphine/naloxone is the preferred opioid substitution treatment for OPD. Our patient remains within her treatment programme and has returned to work on buprenorphine 16 mg/naloxone 4 mg in conjunction with social and psychological support. 2014 BMJ Publishing Group Ltd.

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Year:  2014        PMID: 25519865      PMCID: PMC4275746          DOI: 10.1136/bcr-2014-207458

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  6 in total

1.  Prescription opioid abuse in the UK.

Authors:  Isabelle Giraudon; Karen Lowitz; Paul I Dargan; David M Wood; Richard C Dart
Journal:  Br J Clin Pharmacol       Date:  2013-11       Impact factor: 4.335

2.  Medication-assisted therapies--tackling the opioid-overdose epidemic.

Authors:  Nora D Volkow; Thomas R Frieden; Pamela S Hyde; Stephen S Cha
Journal:  N Engl J Med       Date:  2014-04-23       Impact factor: 91.245

3.  Chronic pain, addiction, and Zohydro.

Authors:  Yngvild Olsen; Joshua M Sharfstein
Journal:  N Engl J Med       Date:  2014-04-23       Impact factor: 91.245

Review 4.  Opioid addiction and abuse in primary care practice: a comparison of methadone and buprenorphine as treatment options.

Authors:  Jean Bonhomme; Ruth S Shim; Richard Gooden; Dawn Tyus; George Rust
Journal:  J Natl Med Assoc       Date:  2012 Jul-Aug       Impact factor: 1.798

Review 5.  Buprenorphine maintenance versus placebo or methadone maintenance for opioid dependence.

Authors:  R P Mattick; J Kimber; C Breen; M Davoli
Journal:  Cochrane Database Syst Rev       Date:  2008-04-16

6.  Changes in opioid and other analgesic use 1995-2010: repeated cross-sectional analysis of dispensed prescribing for a large geographical population in Scotland.

Authors:  A Ruscitto; B H Smith; B Guthrie
Journal:  Eur J Pain       Date:  2014-05-08       Impact factor: 3.931

  6 in total
  3 in total

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Authors:  Jenny L Wilkerson; Sudeshna Ghosh; Mohammed Mustafa; Rehab A Abdullah; Micah J Niphakis; Roberto Cabrera; Rafael L Maldonado; Benjamin F Cravatt; Aron H Lichtman
Journal:  Neuropharmacology       Date:  2016-11-25       Impact factor: 5.250

2.  Development of Pharmacist Independent Prescribing Clinics to Treat Opioid Analgesic Dependence in NHS Lanarkshire.

Authors:  Duncan Hill; Elizabeth Marr; Clair Smith
Journal:  Pharmacy (Basel)       Date:  2019-08-22

3.  How Resistant to Tampering are Codeine Containing Analgesics on the Market? Assessing the Potential for Opioid Extraction.

Authors:  Andreas Kimergård; Paolo Deluca; Peter Hindersson; Torben Breindahl
Journal:  Pain Ther       Date:  2016-06-13
  3 in total

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