| Literature DB >> 2551835 |
Abstract
Uptake of 45Ca was studied in isolated frog retinal pigment epithelial cells. 45Ca accumulation was found to be a saturable, temperature-dependent event. Kinetic analysis of this accumulation revealed two transport systems with apparent km of 2.0 and 0.3 mM. We found the presence of a Na-Ca exchanger mechanism that releases Ca2 under depolarized conditions. Light induced an increase of 45Ca uptake due to activation of the Na-K-ATPase and consequent decrease of extracellular potassium concentration.Entities:
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Year: 1989 PMID： 2551835
Source DB: PubMed Journal: Invest Ophthalmol Vis Sci ISSN： 0146-0404 Impact factor: 4.799