Literature DB >> 25518198

Practice effect and normative data of an HIV-specific neuropsychological testing battery among healthy Thais.

Pasiri Sithinamsuwan, Nicholas Hutchings, Jintanat Ananworanich, Lauren Wendelken, Putthachard Saengtawan, Robert Paul, Nitiya Chomchey, James L K Fletcher, Thep Chalermchai, Victor Valcour.   

Abstract

OBJECTIVE: A longitudinal cohort study was conducted in Bangkok, Thailand between 2008 and 2013 in order to determine the practice effect of serial neuropsychological testing and establish normative data among normal (HIV-uninfected) Thai volunteers. MATERIAL AND
METHOD: The authors enrolled 511 cognitively healthy individuals (HIV-uninfected, no drug abuse or other previous/current neurological or psychological conditions) to assess baseline performance on a HIV-specific neuropsychological testing battery. Ninety-nine subjects were re-assessed at 6 and 12 months to evaluate practice effects.
RESULTS: The mean age of the 99 subjects completing longitudinal visits was 49.2 years and 53 were male. The authors identified improved mean raw scores on most neuropsychological tests with repeated measurements; however only change in WHO Auditory Verbal Learning Test (AVLT) scores (learning, attention, immediate and delayed recall tasks) met statistical significance, with larger differences seen between baseline and 6-month compared to 6 and 12 months follow-up. Older age correlated with poorer baseline raw score, and was a predictor of worse performance at 6 months and 12 months on several tasks. Level of education was associated with practice effects on several tests. No similar effects were observed with gender.
CONCLUSION: The authors identified improved performance after repeated measurements revealing a significant practice effect on an HIV-specific neuropsychological testing battery employed in Bangkok, Thailand. Main predictors were age and educational attainment.

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Year:  2014        PMID: 25518198      PMCID: PMC4324973     

Source DB:  PubMed          Journal:  J Med Assoc Thai        ISSN: 0125-2208


  11 in total

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4.  Test-retest reliability and practice effects of expanded Halstead-Reitan Neuropsychological Test Battery.

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