Literature DB >> 25518045

Cardiac energetic impairment in heart disease and the potential role of metabolic modulators: a review for clinicians.

Satnam Singh1, Konstantin Schwarz1, John Horowitz1, Michael Frenneaux2.   

Abstract

Cardiac energetic impairment is a frequent finding in patients with both inherited and acquired diseases of heart muscle. In this review the mechanisms of energy generation in the healthy heart and their disturbances in heart muscle diseases are described. Therapeutic agents targeted at correcting cardiac energetic impairment are discussed.
© 2014 American Heart Association, Inc.

Entities:  

Keywords:  drug therapy; energy metabolism; perhexiline; reperfusion injury

Mesh:

Substances:

Year:  2014        PMID: 25518045     DOI: 10.1161/CIRCGENETICS.114.000221

Source DB:  PubMed          Journal:  Circ Cardiovasc Genet        ISSN: 1942-3268


  7 in total

Review 1.  Myocardial energy depletion and dynamic systolic dysfunction in hypertrophic cardiomyopathy.

Authors:  Julian O M Ormerod; Michael P Frenneaux; Mark V Sherrid
Journal:  Nat Rev Cardiol       Date:  2016-07-14       Impact factor: 32.419

Review 2.  The Systemic Effects of Exercise on the Systemic Effects of Alzheimer's Disease.

Authors:  Dora Aczel; Bernadett Gyorgy; Peter Bakonyi; RehAn BukhAri; Ricardo Pinho; Istvan Boldogh; Gu Yaodong; Zsolt Radak
Journal:  Antioxidants (Basel)       Date:  2022-05-23

Review 3.  Present and future pharmacotherapeutic agents in heart failure: an evolving paradigm.

Authors:  Brodie L Loudon; Hannah Noordali; Nicholas D Gollop; Michael P Frenneaux; Melanie Madhani
Journal:  Br J Pharmacol       Date:  2016-05-06       Impact factor: 8.739

4.  Study protocol, randomized controlled trial: reducing symptom burden in patients with heart failure with preserved ejection fraction using ubiquinol and/or D-ribose.

Authors:  Janet D Pierce; Diane E Mahoney; John B Hiebert; Amanda R Thimmesch; Francisco J Diaz; Carol Smith; Qiuhua Shen; Dinesh Pal Mudaranthakam; Richard L Clancy
Journal:  BMC Cardiovasc Disord       Date:  2018-04-02       Impact factor: 2.298

5.  Myocardial metabolic alterations in mice with diet-induced atherosclerosis: linking sulfur amino acid and lipid metabolism.

Authors:  Jueun Lee; Sunhee Jung; Nami Kim; Min-Jeong Shin; Do Hyun Ryu; Geum-Sook Hwang
Journal:  Sci Rep       Date:  2017-10-19       Impact factor: 4.379

Review 6.  Nutraceuticals in Chronic Coronary Syndromes: Preclinical Data and Translational Experiences.

Authors:  Chiara Tognola; Maloberti Alessandro; Martina Milani; Iside Cartella; Giovanni Tavecchia; Enzo Grasso; Jinwey Sun; Cristina Giannattasio
Journal:  High Blood Press Cardiovasc Prev       Date:  2020-10-30

7.  The Cardiac Dysfunction Caused by Metabolic Alterations in Alzheimer's Disease.

Authors:  Jiayuan Murphy; Tran Ngoc Van Le; Julia Fedorova; Yi Yang; Meredith Krause-Hauch; Kayla Davitt; Linda Ines Zoungrana; Mohammad Kasim Fatmi; Edward J Lesnefsky; Ji Li; Di Ren
Journal:  Front Cardiovasc Med       Date:  2022-02-22
  7 in total

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