J Furin1, P Isaakidis2, A J Reid3, K Kielmann4. 1. Tuberculosis Research Unit, Case Western Reserve University, Cleveland, Ohio, USA; 2. Médecins Sans Frontières (MSF), Mumbai, India. 3. MSF, Operational Research Unit, Luxembourg. 4. Institute of International Health & Development, Queen Margaret University, Edinburgh, Scotland, UK.
Abstract
OBJECTIVES: To understand the impact of past experiences of anti-tuberculosis treatment among patients co-infected with the human immunodeficiency virus and multidrug-resistant tuberculosis (MDR-TB) on perceptions and attitudes towards treatment. METHODS: Qualitative study using in-depth interviews with 12 HIV-MDR-TB co-infected patients in Mumbai, India. RESULTS: Patients reported unnecessarily long pathways to care and fatigue with diagnostic and treatment procedures. In particular, they expressed concerns over the lack of efficacy of their current treatment regimen based on their experiences with anti-tuberculosis treatment regimens in the past. CONCLUSION: Patients reported negative experiences with previous HIV and anti-tuberculosis treatment. Access to early diagnosis and rapid initiation of integrated care for HIV-MDR-TB co-infected patients, with a strong, patient-centered support system, could help to combat the low morale and lack of faith in treatment described in this group of patients.
OBJECTIVES: To understand the impact of past experiences of anti-tuberculosis treatment among patients co-infected with the human immunodeficiency virus and multidrug-resistant tuberculosis (MDR-TB) on perceptions and attitudes towards treatment. METHODS: Qualitative study using in-depth interviews with 12 HIV-MDR-TB co-infectedpatients in Mumbai, India. RESULTS:Patients reported unnecessarily long pathways to care and fatigue with diagnostic and treatment procedures. In particular, they expressed concerns over the lack of efficacy of their current treatment regimen based on their experiences with anti-tuberculosis treatment regimens in the past. CONCLUSION:Patients reported negative experiences with previous HIV and anti-tuberculosis treatment. Access to early diagnosis and rapid initiation of integrated care for HIV-MDR-TB co-infectedpatients, with a strong, patient-centered support system, could help to combat the low morale and lack of faith in treatment described in this group of patients.
Authors: M R O'Donnell; A Daftary; M Frick; Y Hirsch-Moverman; K R Amico; M Senthilingam; A Wolf; J Z Metcalfe; P Isaakidis; J L Davis; J R Zelnick; J C M Brust; N Naidu; M Garretson; D R Bangsberg; N Padayatchi; G Friedland Journal: Int J Tuberc Lung Dis Date: 2016-04 Impact factor: 2.373
Authors: Kalpita S Shringarpure; Petros Isaakidis; Karuna D Sagili; R K Baxi; Mrinalini Das; Amrita Daftary Journal: PLoS One Date: 2016-03-09 Impact factor: 3.240