Literature DB >> 25517641

Evaluation of patients with Alzheimer's disease before and after dental treatment.

Thaís de Souza Rolim1, Gisele Maria Campos Fabri2, Ricardo Nitrini3, Renato Anghinah3, Manoel Jacobsen Teixeira3, José Tadeu T de Siqueira2, José Augusto Ferrari Cesari1, Silvia Regina Dowgan Tesseroli de Siqueira1.   

Abstract

Oral infections may play a role in Alzheimer's disease (AD). Objective To describe the orofacial pain, dental characteristics and associated factors in patients with Alzheimer's Disease that underwent dental treatment. Method 29 patients with mild AD diagnosed by a neurologist were included. They fulfilled the Mini Mental State Exam and Pfeffer's questionnaire. A dentist performed a complete evaluation: clinical questionnaire; research diagnostic criteria for temporomandibular disorders; McGill pain questionnaire; oral health impact profile; decayed, missing and filled teeth index; and complete periodontal investigation. The protocol was applied before and after the dental treatment. Periodontal treatments (scaling), extractions and topic nystatin were the most frequent. Results There was a reduction in pain frequency (p=0.014), mandibular functional limitations (p=0.011) and periodontal indexes (p<0.05), and an improvement in quality of life (p=0.009) and functional impairment due to cognitive compromise (p<0.001) after the dental treatment. Orofacial complaints and intensity of pain also diminished. Conclusion The dental treatment contributed to reduce co-morbidities associated with AD and should be routinely included in the assessment of these patients.

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Year:  2014        PMID: 25517641     DOI: 10.1590/0004-282X20140140

Source DB:  PubMed          Journal:  Arq Neuropsiquiatr        ISSN: 0004-282X            Impact factor:   1.420


  14 in total

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Journal:  Int J Health Sci (Qassim)       Date:  2016-04

2.  Correlation of cognitive and masticatory function in Alzheimer's disease.

Authors:  Camila Heitor Campos; Giselle Rodrigues Ribeiro; José Luiz Riani Costa; Renata Cunha Matheus Rodrigues Garcia
Journal:  Clin Oral Investig       Date:  2016-07-30       Impact factor: 3.573

3.  Intranasal midazolam for the sedation of geriatric patients with care-resistant behaviour during essential dental treatment: An observational study.

Authors:  Clemens R M Barends; Anthony R Absalom; Anita Visser
Journal:  Gerodontology       Date:  2021-03-21       Impact factor: 2.750

4.  Periodontitis and Cognitive Decline in Alzheimer's Disease.

Authors:  Mark Ide; Marina Harris; Annette Stevens; Rebecca Sussams; Viv Hopkins; David Culliford; James Fuller; Paul Ibbett; Rachel Raybould; Rhodri Thomas; Ursula Puenter; Jessica Teeling; V Hugh Perry; Clive Holmes
Journal:  PLoS One       Date:  2016-03-10       Impact factor: 3.240

Review 5.  Oral health and orofacial pain in older people with dementia: a systematic review with focus on dental hard tissues.

Authors:  Suzanne Delwel; Tarik T Binnekade; Roberto S G M Perez; Cees M P M Hertogh; Erik J A Scherder; Frank Lobbezoo
Journal:  Clin Oral Investig       Date:  2016-09-08       Impact factor: 3.573

Review 6.  Oral hygiene and oral health in older people with dementia: a comprehensive review with focus on oral soft tissues.

Authors:  Suzanne Delwel; Tarik T Binnekade; Roberto S G M Perez; Cees M P M Hertogh; Erik J A Scherder; Frank Lobbezoo
Journal:  Clin Oral Investig       Date:  2017-11-15       Impact factor: 3.573

Review 7.  Potential Bidirectional Relationship Between Periodontitis and Alzheimer's Disease.

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Journal:  Front Physiol       Date:  2020-07-03       Impact factor: 4.566

Review 8.  Research on the Glial-Lymphatic System and Its Relationship With Alzheimer's Disease.

Authors:  Danhua Ding; Xinyu Wang; Qianqian Li; Lanjun Li; Jun Wu
Journal:  Front Neurosci       Date:  2021-06-16       Impact factor: 4.677

9.  Diurnal dynamic behavior of microglia in response to infected bacteria through the UDP-P2Y6 receptor system.

Authors:  Fumiko Takayama; Yoshinori Hayashi; Zhou Wu; Yicong Liu; Hiroshi Nakanishi
Journal:  Sci Rep       Date:  2016-07-21       Impact factor: 4.379

Review 10.  Oral health in China: from vision to action.

Authors:  Xuedong Zhou; Xin Xu; Jiyao Li; Deyu Hu; Tao Hu; Wei Yin; Yujiang Fan; Xingdong Zhang
Journal:  Int J Oral Sci       Date:  2018-01-17       Impact factor: 6.344

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