Literature DB >> 25517462

Developing stem cell therapies for Parkinson's disease: waiting until the time is right.

Roger A Barker1.   

Abstract

The ability to successfully replace lost nigral dopaminergic neurons in Parkinson's disease (PD) has been clearly shown with fetal ventral mesencephalic transplants, albeit inconsistently. The need to trial this approach with stem-cell-derived neurons is approaching, but it should only commence when all the key issues have been adequately resolved.
Copyright © 2014 Elsevier Inc. All rights reserved.

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Year:  2014        PMID： 25517462     DOI： 10.1016/j.stem.2014.09.016

Source DB:  PubMed          Journal:  Cell Stem Cell        ISSN： 1875-9777            Impact factor:   24.633


  17 in total

1.  Real-Time Intraoperative MRI Intracerebral Delivery of Induced Pluripotent Stem Cell-Derived Neurons.

Authors:  Scott C Vermilyea; Jianfeng Lu; Miles Olsen; Scott Guthrie; Yunlong Tao; Eva M Fekete; Marissa K Riedel; Kevin Brunner; Carissa Boettcher; Viktorya Bondarenko; Ethan Brodsky; Walter F Block; Andrew Alexander; Su-Chun Zhang; Marina E Emborg
Journal:  Cell Transplant       Date:  2016-09-14       Impact factor: 4.064

Review 2.  Neurodegenerative Disease: A Perspective on Cell-Based Therapy in the New Era of Cell-Free Nano-Therapy.

Authors:  Su M Metcalfe; Sean Bickerton; Tarek Fahmy
Journal:  Curr Pharm Des       Date:  2017       Impact factor: 3.116

Review 3.  Adapting Preclinical Benchmarks for First-in-Human Trials of Human Embryonic Stem Cell-Based Therapies.

Authors:  Gaia Barazzetti; Samia A Hurst; Alexandre Mauron
Journal:  Stem Cells Transl Med       Date:  2016-06-22       Impact factor: 6.940

Review 4.  Cell-based therapies for Parkinson disease—past insights and future potential.

Authors:  Roger A Barker; Janelle Drouin-Ouellet; Malin Parmar
Journal:  Nat Rev Neurol       Date:  2015-08-04       Impact factor: 42.937

5.  Human ESC-derived dopamine neurons show similar preclinical efficacy and potency to fetal neurons when grafted in a rat model of Parkinson's disease.

Authors:  Shane Grealish; Elsa Diguet; Agnete Kirkeby; Bengt Mattsson; Andreas Heuer; Yann Bramoulle; Nadja Van Camp; Anselme L Perrier; Philippe Hantraye; Anders Björklund; Malin Parmar
Journal:  Cell Stem Cell       Date:  2014-11-06       Impact factor: 24.633

6.  Grafted Neural Precursors Integrate Into Mouse Striatum, Differentiate and Promote Recovery of Function Through Release of Erythropoietin in MPTP-Treated Mice.

Authors:  Stephana Carelli; Toniella Giallongo; Cristina Viaggi; Zuzana Gombalova; Elisa Latorre; Massimiliano Mazza; Francesca Vaglini; Anna Maria Di Giulio; Alfredo Gorio
Journal:  ASN Neuro       Date:  2016-10-27       Impact factor: 4.146

7.  Icariside II promotes the differentiation of human amniotic mesenchymal stem cells into dopaminergic neuron-like cells.

Authors:  Wei Kuang; Tao Liu; Fang He; Limei Yu; Qian Wang; Changyin Yu
Journal:  In Vitro Cell Dev Biol Anim       Date:  2021-03-15       Impact factor: 2.416

Review 8.  Induced Pluripotent Stem Cell Therapies for Cervical Spinal Cord Injury.

Authors:  Vanessa M Doulames; Giles W Plant
Journal:  Int J Mol Sci       Date:  2016-04-09       Impact factor: 5.923

Review 9.  Neuroprotective and Therapeutic Strategies against Parkinson's Disease: Recent Perspectives.

Authors:  Sumit Sarkar; James Raymick; Syed Imam
Journal:  Int J Mol Sci       Date:  2016-06-08       Impact factor: 5.923

10.  Are Stem Cell-Based Therapies for Parkinson's Disease Ready for the Clinic in 2016?

Authors:  Roger A Barker; Malin Parmar; Agnete Kirkeby; Anders Björklund; Lachlan Thompson; Patrik Brundin
Journal:  J Parkinsons Dis       Date:  2016       Impact factor: 5.568
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