Literature DB >> 25516792

Synthesis and Characterization of a "Turn-On" photoCORM for Trackable CO Delivery to Biological Targets.

Samantha J Carrington1, Indranil Chakraborty1, Jenna M L Bernard2, Pradip K Mascharak1.   

Abstract

A designed photoactive CO releasing molecule (photoCORM), namely, fac-[MnBr(CO)3(pbt)] (1, pbt = 2-(2-pyridyl)benzothiazole), promotes CO-induced death of MDA-MB-231 human breast cancer cells upon illumination with broadband visible light. The CO release from this photoCORM can be tracked by rise in fluorescence within the cellular matrix due to deligation of the pbt ligand. The results of this study suggest the potential of 1 in eradication of cancer cells through CO delivery.

Entities:  

Keywords:  CO delivery; Carbon monoxide; apoptosis; fluorescence tracking; photoactive metal carbonyls

Year:  2014        PMID： 25516792      PMCID： PMC4265820          DOI： 10.1021/ml500399r

Source DB:  PubMed          Journal:  ACS Med Chem Lett        ISSN： 1948-5875            Impact factor:   4.345


  24 in total

1.  Chemistry and biological activities of CO-releasing molecules (CORMs) and transition metal complexes.

Authors:  Roger Alberto; Roberto Motterlini
Journal:  Dalton Trans       Date:  2007-04-03       Impact factor: 4.390

2.  Benzothiazoles exhibit broad-spectrum antitumor activity: their potency, structure-activity and structure-metabolism relationships.

Authors:  Xilei Xie; Yu Yan; Ning Zhu; Gang Liu
Journal:  Eur J Med Chem       Date:  2014-02-07       Impact factor: 6.514

Review 3.  CO as a cellular signaling molecule.

Authors:  Hong Pyo Kim; Stefan W Ryter; Augustine M K Choi
Journal:  Annu Rev Pharmacol Toxicol       Date:  2006       Impact factor: 13.820

4.  Administration of a CO-releasing molecule induces late preconditioning against myocardial infarction.

Authors:  Adam B Stein; Yiru Guo; Wei Tan; Wen-Jian Wu; Xiaoping Zhu; Qianhong Li; Cheng Luo; Buddhadeb Dawn; Tony R Johnson; Roberto Motterlini; Roberto Bolli
Journal:  J Mol Cell Cardiol       Date:  2004-12-08       Impact factor: 5.000

5.  Carbon monoxide promotes Fas/CD95-induced apoptosis in Jurkat cells.

Authors:  Ruiping Song; Zhihong Zhou; Peter K M Kim; Richard A Shapiro; Fang Liu; Christiane Ferran; Augustine M K Choi; Leo E Otterbein
Journal:  J Biol Chem       Date:  2004-07-27       Impact factor: 5.157

6.  Design strategies to improve the sensitivity of photoactive metal carbonyl complexes (photoCORMs) to visible light and their potential as CO-donors to biological targets.

Authors:  Indranil Chakraborty; Samantha J Carrington; Pradip K Mascharak
Journal:  Acc Chem Res       Date:  2014-07-08       Impact factor: 22.384

7.  Photoinduced CO release, cellular uptake and cytotoxicity of a tris(pyrazolyl)methane (tpm) manganese tricarbonyl complex.

Authors:  Johanna Niesel; Antonio Pinto; Harmel W Peindy N'Dongo; Klaus Merz; Ingo Ott; Ronald Gust; Ulrich Schatzschneider
Journal:  Chem Commun (Camb)       Date:  2008-02-08       Impact factor: 6.222

8.  Rapid CO release from a Mn(I) carbonyl complex derived from azopyridine upon exposure to visible light and its phototoxicity toward malignant cells.

Authors:  Samantha J Carrington; Indranil Chakraborty; Pradip K Mascharak
Journal:  Chem Commun (Camb)       Date:  2013-10-01       Impact factor: 6.222

9.  Carbon monoxide expedites metabolic exhaustion to inhibit tumor growth.

Authors:  Barbara Wegiel; David Gallo; Eva Csizmadia; Clair Harris; John Belcher; Gregory M Vercellotti; Nuno Penacho; Pankaj Seth; Vikas Sukhatme; Asif Ahmed; Pier Paolo Pandolfi; Leszek Helczynski; Anders Bjartell; Jenny Liao Persson; Leo E Otterbein
Journal:  Cancer Res       Date:  2013-10-11       Impact factor: 12.701

Review 10.  Protective effect of carbon monoxide in transplantation.

Authors:  Atsunori Nakao; Augustine M K Choi; Noriko Murase
Journal:  J Cell Mol Med       Date:  2006 Jul-Sep       Impact factor: 5.310
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  13 in total

1.  Light-triggered CO delivery by a water-soluble and biocompatible manganese photoCORM.

Authors:  Jorge Jimenez; Indranil Chakraborty; Samantha J Carrington; Pradip K Mascharak
Journal:  Dalton Trans       Date:  2016-08-16       Impact factor: 4.390

2.  Visible-to-NIR-Light Activated Release: From Small Molecules to Nanomaterials.

Authors:  Roy Weinstain; Tomáš Slanina; Dnyaneshwar Kand; Petr Klán
Journal:  Chem Rev       Date:  2020-10-30       Impact factor: 60.622

3.  Photoactivated in Vitro Anticancer Activity of Rhenium(I) Tricarbonyl Complexes Bearing Water-Soluble Phosphines.

Authors:  Sierra C Marker; Samantha N MacMillan; Warren R Zipfel; Zhi Li; Peter C Ford; Justin J Wilson
Journal:  Inorg Chem       Date:  2018-01-11       Impact factor: 5.165

4.  Visible-Light-Activated Quinolone Carbon-Monoxide-Releasing Molecule: Prodrug and Albumin-Assisted Delivery Enables Anticancer and Potent Anti-Inflammatory Effects.

Authors:  Marina Popova; Tatiana Soboleva; Suliman Ayad; Abby D Benninghoff; Lisa M Berreau
Journal:  J Am Chem Soc       Date:  2018-07-23       Impact factor: 15.419

5.  Tracking CO release in cells via the luminescence of donor molecules and/or their by-products.

Authors:  Tatiana Soboleva; Lisa M Berreau
Journal:  Isr J Chem       Date:  2019-02-11       Impact factor: 3.333

6.  Phototriggered cytotoxic properties of tricarbonyl manganese(I) complexes bearing α-diimine ligands towards HepG2.

Authors:  Ahmed M Mansour; Krzysztof Radacki; Rabaa M Khaled; Marwa H Soliman; Nour T Abdel-Ghani
Journal:  J Biol Inorg Chem       Date:  2021-02-27       Impact factor: 3.358

7.  Synthesis and assessment of CO-release capacity of manganese carbonyl complexes derived from rigid α-diimine ligands of varied complexity.

Authors:  Jorge Jimenez; Indranil Chakraborty; Pradip K Mascharak
Journal:  Eur J Inorg Chem       Date:  2015-09-30       Impact factor: 2.524

8.  Chemical Reactivities of Two Widely Used Ruthenium-Based CO-Releasing Molecules with a Range of Biologically Important Reagents and Molecules.

Authors:  Zhengnan Yuan; Xiaoxiao Yang; Yuqian Ye; Ravi Tripathi; Binghe Wang
Journal:  Anal Chem       Date:  2021-03-21       Impact factor: 6.986

Review 9.  Aspects of Carbon Monoxide in Form of CO-Releasing Molecules Used in Cancer Treatment: More Light on the Way.

Authors:  Malamati Kourti; Wen G Jiang; Jun Cai
Journal:  Oxid Med Cell Longev       Date:  2017-02-13       Impact factor: 6.543

10.  Light-Activated Carbon Monoxide Prodrugs Based on Bipyridyl Dicarbonyl Ruthenium(II) Complexes.

Authors:  Stepan Geri; Tereza Krunclova; Olga Janouskova; Jiri Panek; Martin Hruby; Daniel Hernández-Valdés; Benjamin Probst; Roger A Alberto; Constantin Mamat; Manja Kubeil; Holger Stephan
Journal:  Chemistry       Date:  2020-08-13       Impact factor: 5.236
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