AIM: To review and conduct a meta-analysis of the existing literature on the relationship between Helicobacter pylori (H. pylori), atopy and allergic diseases. METHODS: Studies published in English assessing the prevalence of atopy and/or allergic diseases in patients with H. pylori infection and the prevalence of H. pylori infection in patients with atopy and/or allergic diseases were identified through a MEDLINE search (1950-2014). Random-effect model was used for the meta-analysis. RESULTS: Pooled results of case-control studies showed a significant inverse association of H. pylori infection with atopy/allergic disease or with exclusively atopy, but not with allergic disease, whereas pooled results of cross-sectional studies showed only a significant association between allergic disease and H. pylori infection. CONCLUSION: There is some evidence of an inverse association between atopy/allergic diseases and H. pylori infection, although further studied are needed.
AIM: To review and conduct a meta-analysis of the existing literature on the relationship between Helicobacter pylori (H. pylori), atopy and allergic diseases. METHODS: Studies published in English assessing the prevalence of atopy and/or allergic diseases in patients with H. pyloriinfection and the prevalence of H. pyloriinfection in patients with atopy and/or allergic diseases were identified through a MEDLINE search (1950-2014). Random-effect model was used for the meta-analysis. RESULTS: Pooled results of case-control studies showed a significant inverse association of H. pyloriinfection with atopy/allergic disease or with exclusively atopy, but not with allergic disease, whereas pooled results of cross-sectional studies showed only a significant association between allergic disease and H. pyloriinfection. CONCLUSION: There is some evidence of an inverse association between atopy/allergic diseases and H. pyloriinfection, although further studied are needed.
Authors: P Cullinan; J M Harris; A J Newman Taylor; M Jones; P Taylor; J R Dave; P Mills; S A Moffat; C W White; J K Figg; A M Moon; M C Barnes Journal: Eur Respir J Date: 2003-12 Impact factor: 16.671
Authors: K Radon; D Windstetter; J Eckart; H Dressel; L Leitritz; J Reichert; M Schmid; G Praml; M Schosser; E von Mutius; D Nowak Journal: Clin Exp Allergy Date: 2004-08 Impact factor: 5.018
Authors: Jing Yang; Qiang Zhang; Ming Chen; Wu-zhou Wu; Rong Wang; Chang-jun Liu; Bei Li; Xin-li Shi; Han-song Du; Hua-bing Tan Journal: Med Sci Monit Date: 2016-01-12