Literature DB >> 25516486

The effect of solvent choice on the gelation and final hydrogel properties of Fmoc-diphenylalanine.

Jaclyn Raeburn1, Cristina Mendoza-Cuenca, Beatrice N Cattoz, Marc A Little, Ann E Terry, Andre Zamith Cardoso, Peter C Griffiths, Dave J Adams.   

Abstract

Gels can be formed by dissolving Fmoc-diphenylalanine (Fmoc-PhePhe or FmocFF) in an organic solvent and adding water. We show here that the choice and amount of organic solvent allows the rheological properties of the gel to be tuned. The differences in properties arise from the microstructure of the fibre network formed. The organic solvent can then be removed post-gelation, without significant changes in the rheological properties. Gels formed using acetone are meta-stable and crystals of FmocFF suitable for X-ray diffraction can be collected from this gel.

Entities:  

Year:  2015        PMID: 25516486     DOI: 10.1039/c4sm02256d

Source DB:  PubMed          Journal:  Soft Matter        ISSN: 1744-683X            Impact factor:   3.679


  16 in total

Review 1.  Supramolecular Hydrogelators and Hydrogels: From Soft Matter to Molecular Biomaterials.

Authors:  Xuewen Du; Jie Zhou; Junfeng Shi; Bing Xu
Journal:  Chem Rev       Date:  2015-12-08       Impact factor: 60.622

2.  High-Strength, Durable All-Silk Fibroin Hydrogels with Versatile Processability toward Multifunctional Applications.

Authors:  Zhenghua Zhu; Shengjie Ling; Jingjie Yeo; Siwei Zhao; Lorenzo Tozzi; Markus J Buehler; Fiorenzo Omenetto; Chunmei Li; David L Kaplan
Journal:  Adv Funct Mater       Date:  2018-01-08       Impact factor: 18.808

3.  Molecular Engineering of Rigid Hydrogels Co-assembled from Collagenous Helical Peptides Based on a Single Triplet Motif.

Authors:  Santu Bera; Pierre-Andre Cazade; Shayon Bhattacharya; Sarah Guerin; Moumita Ghosh; Francesca Netti; Damien Thompson; Lihi Adler-Abramovich
Journal:  ACS Appl Mater Interfaces       Date:  2022-10-07       Impact factor: 10.383

4.  The Enzyme-instructed assembly of the core of yeast prion Sup35 to form supramolecular hydrogels.

Authors:  Dan Yuan; Junfeng Shi; Xuewen Du; Yibing Huang; Yuan Gao; Bing Xu
Journal:  J Mater Chem B       Date:  2016-01-11       Impact factor: 6.331

5.  Design and Evaluation of Short Self-Assembling Depsipeptides as Bioactive and Biodegradable Hydrogels.

Authors:  Kevin M Eckes; Kiheon Baek; Laura J Suggs
Journal:  ACS Omega       Date:  2018-02-08

Review 6.  Hydrogels Based Drug Delivery Synthesis, Characterization and Administration.

Authors:  Anca Onaciu; Raluca Andrada Munteanu; Alin Iulian Moldovan; Cristian Silviu Moldovan; Ioana Berindan-Neagoe
Journal:  Pharmaceutics       Date:  2019-08-23       Impact factor: 6.321

7.  Expanding the Functional Scope of the Fmoc-Diphenylalanine Hydrogelator by Introducing a Rigidifying and Chemically Active Urea Backbone Modification.

Authors:  Vasantha Basavalingappa; Tom Guterman; Yiming Tang; Sivan Nir; Jiangtao Lei; Priyadarshi Chakraborty; Lee Schnaider; Meital Reches; Guanghong Wei; Ehud Gazit
Journal:  Adv Sci (Weinh)       Date:  2019-04-19       Impact factor: 16.806

8.  On the Mechanical Properties of N-Functionalised Dipeptide Gels.

Authors:  Ana M Fuentes-Caparrós; Kate McAulay; Sarah E Rogers; Robert M Dalgliesh; Dave J Adams
Journal:  Molecules       Date:  2019-10-25       Impact factor: 4.411

9.  Exploiting and controlling gel-to-crystal transitions in multicomponent supramolecular gels.

Authors:  Demetra Giuri; Libby J Marshall; Bart Dietrich; Daniel McDowall; Lisa Thomson; Jenny Y Newton; Claire Wilson; Ralf Schweins; Dave J Adams
Journal:  Chem Sci       Date:  2021-06-14       Impact factor: 9.825

10.  Spontaneous structural transition and crystal formation in minimal supramolecular polymer model.

Authors:  Galit Fichman; Tom Guterman; Joshua Damron; Lihi Adler-Abramovich; Judith Schmidt; Ellina Kesselman; Linda J W Shimon; Ayyalusamy Ramamoorthy; Yeshayahu Talmon; Ehud Gazit
Journal:  Sci Adv       Date:  2016-02-12       Impact factor: 14.136

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