Literature DB >> 2551494

Chromosomal changes in human primary testicular nonseminomatous germ cell tumors.

S M Castedo1, B de Jong, J W Oosterhuis, R Seruca, V J Idenburg, A Dam, G te Meerman, H S Koops, D T Sleijfer.   

Abstract

A cytogenetic analysis of 14 primary testicular nonseminomatous germ cell tumors has been carried out after short term tissue culture. The modal chromosome numbers ranged from 53 to 113, in agreement with flow cytometric determination of the DNA content of the tumors. At least one copy of an i(12p) was present in 12 tumors. Two tumors, however, lacked that marker. Some chromosomes are apparently overrepresented, whereas others are underrepresented, although some differences between seminomas and nonseminomas were noticed.

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Year:  1989        PMID： 2551494

Source DB:  PubMed          Journal:  Cancer Res        ISSN： 0008-5472            Impact factor:   12.701


  9 in total

1.  Restricted 12p amplification and RAS mutation in human germ cell tumors of the adult testis.

Authors:  H Roelofs; M C Mostert; K Pompe; G Zafarana; M van Oorschot; R J van Gurp; A J Gillis; H Stoop; B Beverloo; J W Oosterhuis; C Bokemeyer; L H Looijenga
Journal:  Am J Pathol       Date:  2000-10       Impact factor: 4.307

2.  Familial/bilateral and sporadic testicular germ cell tumors show frequent genetic changes at loci with suggestive linkage evidence.

Authors:  R I Skotheim; S M Kraggerud; S D Fosså; A E Stenwig; T Gedde-Dahl ; H E Danielsen; K S Jakobsen; R A Lothe
Journal:  Neoplasia       Date:  2001 May-Jun       Impact factor: 5.715

3.  Mediastinal germ cell tumors: many questions and perhaps an answer.

Authors:  J Wolter Oosterhuis; Leendert Hj Looijenga
Journal:  J Clin Invest       Date:  2020-12-01       Impact factor: 14.808

4.  Hypermethylation of the RUNX3 gene promoter in testicular yolk sac tumor of infants.

Authors:  Noriko Kato; Gen Tamura; Masayuki Fukase; Hiroyuki Shibuya; Teiichi Motoyama
Journal:  Am J Pathol       Date:  2003-08       Impact factor: 4.307

5.  Serum lactate dehydrogenase isoenzyme 1 activity in patients with testicular germ cell tumors correlates with the total number of copies of the short arm of chromosome 12 in the tumor.

Authors:  F E von Eyben; W E de Graaff; J Marrink; O Blaabjerg; D T Sleijfer; H S Koops; J W Oosterhuis; P H Petersen; J van Echten-Arends; B de Jong
Journal:  Mol Gen Genet       Date:  1992-10

6.  Molecular cytogenetic analysis of adult testicular germ cell tumours and identification of regions of consensus copy number change.

Authors:  B Summersgill; H Goker; S Weber-Hall; R Huddart; A Horwich; J Shipley
Journal:  Br J Cancer       Date:  1998       Impact factor: 7.640

7.  Allelic losses in carcinoma in situ and testicular germ cell tumours of adolescents and adults: evidence suggestive of the linear progression model.

Authors:  S W Faulkner; D A Leigh; J W Oosterhuis; H Roelofs; L H Looijenga; M L Friedlander
Journal:  Br J Cancer       Date:  2000-09       Impact factor: 7.640

8.  Mature teratoma as a perineal mass:Unusal presentation.

Authors:  Seyed Reza Hosseini
Journal:  Urol Case Rep       Date:  2022-05-01

9.  Identification of Novel Fusion Genes in Testicular Germ Cell Tumors.

Authors:  Andreas M Hoff; Sharmini Alagaratnam; Sen Zhao; Jarle Bruun; Peter W Andrews; Ragnhild A Lothe; Rolf I Skotheim
Journal:  Cancer Res       Date:  2015-12-09       Impact factor: 12.701
  9 in total

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