Jie Zhang1, Hang Su2, Jingyan Tao2, Ying Xie2, Yeming Sun3, Liren Li4, Xiang Yang Zhang5, Zhenyu Hu6, Jincai He7. 1. Department of Neurology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou 325000, PR China; Department of Neurology, Taizhou Municipal Hospital, Taizhou 317700, PR China. 2. Department of Neurology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou 325000, PR China. 3. Department of Psychiatry, New Jersey Medical School, Rutgers University, NJ 07103, USA. 4. Department of Psychiatry, Robert Wood Johnson Medical School, Rutgers University, NJ 08901, USA. 5. Beijing HuiLongGuan Hospital, Peking University, Beijing 100096, PR China; Menninger Department of Psychiatry and Behavioral Sciences, Baylor College of Medicine, Houston, TX 77030, USA. Electronic address: xyzhang@bcm.edu. 6. Department of Psychological Counseling, Ningbo Kangning Hospital, Ningbo, 315201, PR China. Electronic address: hzy86690592@163.com. 7. Department of Neurology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou 325000, PR China. Electronic address: hjc@wzmc.edu.cn.
Abstract
OBJECTIVE: High level of impulsivity as well as depression is thought to be involved in the maintenance and development of methamphetamine (METH) addiction. However, the relationship between impulsivity and depression has not been studied thoroughly in METH dependence subjects, especially in early METH abstinent subjects. In this study, our objective is to explore the interplay between the depressive symptoms and impulsivity in early METH abstinent subjects. METHODS: A total of 182 early abstinent METH dependent subjects (abstinence for 1-7 days) were recruited and the level of impulsivity was measured by the Barratt Impulsiveness Scale (BIS-11). Depressive symptoms and anxiety symptoms were assessed by the short 13-item Beck Depression Inventory (BDI-13) and Beck Anxiety Inventory (BAI) respectively. RESULTS: Global impulsivity of BIS-11 was significantly correlated with depressive symptoms among early METH abstinent subjects (r=0.283, p=0.001). Moreover, all subscales of BIS-11 were also found to be correlated with depressive symptoms: correlation with attentional impulsivity (r=0.202, p=0.006); correlation with motor impulsivity (r=0.267, p=0.001); and correlation with non-planning impulsivity (r=0.177, p=0.017). CONCLUSIONS: This study showed a relationship between impulsivity and depression, which may further the comprehension of motivational elements contributing to the maintenance and development of METH use disorder. Future research would be dedicated to exploring underlying mechanisms of association between impulsivity and depression.
OBJECTIVE: High level of impulsivity as well as depression is thought to be involved in the maintenance and development of methamphetamine (METH) addiction. However, the relationship between impulsivity and depression has not been studied thoroughly in METH dependence subjects, especially in early METH abstinent subjects. In this study, our objective is to explore the interplay between the depressive symptoms and impulsivity in early METH abstinent subjects. METHODS: A total of 182 early abstinent METH dependent subjects (abstinence for 1-7 days) were recruited and the level of impulsivity was measured by the Barratt Impulsiveness Scale (BIS-11). Depressive symptoms and anxiety symptoms were assessed by the short 13-item Beck Depression Inventory (BDI-13) and Beck Anxiety Inventory (BAI) respectively. RESULTS: Global impulsivity of BIS-11 was significantly correlated with depressive symptoms among early METH abstinent subjects (r=0.283, p=0.001). Moreover, all subscales of BIS-11 were also found to be correlated with depressive symptoms: correlation with attentional impulsivity (r=0.202, p=0.006); correlation with motor impulsivity (r=0.267, p=0.001); and correlation with non-planning impulsivity (r=0.177, p=0.017). CONCLUSIONS: This study showed a relationship between impulsivity and depression, which may further the comprehension of motivational elements contributing to the maintenance and development of METH use disorder. Future research would be dedicated to exploring underlying mechanisms of association between impulsivity and depression.
Authors: Bosco C Rowland; Mohammadreza Mohebbi; Adrian B Kelly; Michelle L Benstead; Jess A Herde; Elizabeth M Clancy; Jennifer A Bailey; Bill Hallam; Paul Sharkey; Robyn Horner; John W Toumbourou Journal: J Relig Health Date: 2022-03-14
Authors: Jan Szczypiński; Andrzej Jakubczyk; Maciej Kopera; Elisa Trucco; Marcin Wojnar Journal: Drug Alcohol Depend Date: 2021-06-18 Impact factor: 4.852